SCHEMBL1047606

SCHEMBL1047606

CCC(C)C(O)CC(O)CC(=O)O

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.48
GPR84 Q9NQS5 4/20 0.42
MAPT P10636 1/20 0.42
GABRR1 P24046 2/20 0.41
LMNA P02545 1/20 0.41
CACNA2D1 P54289 2/20 0.35
CACNB3 P54284 1/20 0.35
CACNA1C Q13936 1/20 0.35
PGR P06401 1/20 0.35
ADRA1A P35348 1/20 0.35
HTR2B P41595 1/20 0.35
CACNA2D2 Q9NY47 1/20 0.35
MME P08473 1/20 0.35
ACE P12821 1/20 0.35
CPA1 P15085 1/20 0.35
ACE2 Q9BYF1 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26106950 1.00 SLC22A6 (0.48) SLC22A6GPR84MAPTGABRR1LMNA
SCHEMBL26107220 0.84 POLB (0.38) SLC22A6GPR84MAPTGABRR1LMNA
SCHEMBL26107221 0.84 POLB (0.38) SLC22A6GPR84MAPTGABRR1LMNA
SCHEMBL7378347 0.82 MME (0.44) SLC22A6GPR84MAPTGABRR1LMNA
SCHEMBL667935 0.82 MME (0.44) SLC22A6GPR84MAPTGABRR1LMNA
SCHEMBL4748392 0.82 MME (0.44) SLC22A6GPR84MAPTGABRR1LMNA
SCHEMBL14606193 0.81 SLC22A6 (0.50) SLC22A6GPR84MAPTGABRR1LMNA
SCHEMBL16600216 0.80 SLC22A6 (0.55) SLC22A6GPR84MAPTGABRR1LMNA
SCHEMBL14189817 0.80 SLC22A6 (0.55) SLC22A6GPR84MAPTGABRR1LMNA
SCHEMBL25181478 0.78 SLC22A6 (0.52) SLC22A6GPR84MAPTGABRR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 249 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260000783-A1 ANTIBODY-DRUG CONJUGATE WITH IMPROVED THERAPEUTIC WINDOW SAPREME TECHNOLOGIES B.V. (NL) 2026-01-01 US claimed
EP-4647436-A2 BIOLOGICALLY ACTIVE CLUSTER OF MOLECULES Sapreme Technologies B.V. (NL) 2025-11-12 EP claimed
EP-4635515-A2 CONJUGATE OF A SINGLE DOMAIN ANTIBODY, A SAPONIN AND AN EFFECTOR MOLECULE, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, THERAPEUTIC USE OF SAID PHARMACEUTICAL COMPOSITION Sapreme Technologies B.V. (NL) 2025-10-22 EP claimed
EP-3897735-B1 BIOLOGICALLY ACTIVE CLUSTER OF MOLECULES SAPREME TECH BV (NL) 2025-10-22 EP claimed
EP-4635501-A2 SAPONIN DERIVATIVES WITH IMPROVED THERAPEUTIC WINDOW Sapreme Technologies B.V. (NL) 2025-10-22 EP claimed
EP-4631524-A2 COMBINATION COMPRISING AN ADC OR AN AOC COMPRISING A VHH, AND A SAPONIN OR A LIGAND-SAPONIN CONJUGATE Sapreme Technologies B.V. (NL) 2025-10-15 EP claimed
US-20250295800-A1 CONJUGATE OF A SINGLE DOMAIN ANTIBODY, A SAPONIN AND AN EFFECTOR MOLECULE, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, THERAPEUTIC USE OF SAID PHARMACEUTICAL COMPOSITION SAPREME TECH BV (NL) 2025-09-25 US claimed
EP-4210761-B1 SEMICARBAZONE-BASED SAPONIN CONJUGATE SAPREME TECH BV (NL) 2025-08-20 EP claimed
EP-4596052-A2 THERAPEUTIC COMBINATION OF GALNAC-OLIGONUCLEOTIDE CONJUGATE AND SAPONIN, AND USES THEREOF Sapreme Technologies B.V. (NL) 2025-08-06 EP claimed
EP-4591938-A2 CONJUGATE OF SAPONIN, OLIGONUCLEOTIDE AND GALNAC Sapreme Technologies B.V. (NL) 2025-07-30 EP claimed
WO-2022055352-A1 SEMICARBAZONE-BASED SAPONIN CONJUGATE SAPREME TECHNOLOGIES B.V. (NL) 2022-03-17 WO claimed
EP-3897735-A1 BIOLOGICALLY ACTIVE CLUSTER OF MOLECULES SAPREME TECHNOLOGIES B.V. (NL) 2021-10-27 EP claimed
EP-3897741-A1 IMPROVED CELL-TARGETING BINDING MOLECULE SAPREME TECHNOLOGIES B.V. (NL) 2021-10-27 EP claimed
EP-3856254-A2 IMPROVED ANTIBODY-OLIGONUCLEOTIDE CONJUGATE SAPREME TECHNOLOGIES B.V. (NL) 2021-08-04 EP claimed
EP-3773737-A1 SAPONIN CONJUGATED TO EPITOPE-BINDING PROTEINS SAPREME TECHNOLOGIES B.V. (NL) 2021-02-17 EP claimed
WO-2020126620-A2 IMPROVED ANTIBODY-OLIGONUCLEOTIDE CONJUGATE SAPREME TECHNOLOGIES B.V. (NL) 2020-06-25 WO claimed
WO-2020126626-A1 BIOLOGICALLY ACTIVE CLUSTER OF MOLECULES SAPREME TECHNOLOGIES B.V. (NL) 2020-06-25 WO claimed
WO-2020126064-A1 SAPONIN CONJUGATED TO EPITOPE-BINDING PROTEINS SAPREME TECHNOLOGIES B.V. (NL) 2020-06-25 WO claimed
WO-2020126627-A1 IMPROVED CELL-TARGETING BINDING MOLECULE SAPREME TECHNOLOGIES B.V. (NL) 2020-06-25 WO claimed
US-20110020226-A1 PARTICLE STRUCTURES COMPRISING STEROLS AND SAPONINS NORDIC VACCINE TECHNOLOGY A/S 2011-01-27 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110020226-A1 PARTICLE STRUCTURES COMPRISING STEROLS AND SAPONINS LSS, SNRPE, HLA-C SLC22A6 2138/4885GPR84 675/4885MAPT 4825/4885
US-20260000783-A1 ANTIBODY-DRUG CONJUGATE WITH IMPROVED THERAPEUTIC WINDOW EPCAM, CD47, FCGR3B SLC22A6 2453/4885GPR84 1804/4885MAPT 3753/4885
US-20250295800-A1 CONJUGATE OF A SINGLE DOMAIN ANTIBODY, A SAPONIN AND AN EFFECTOR MOLECULE, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, THERAPEUTIC USE OF SAID PHARMACEUTICAL COMPOSITION CYP46A1, HCCS, DHCR7 SLC22A6 1764/4885GPR84 4189/4885MAPT 2011/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.