Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 4/20 | 0.36 |
| ▸ | CNR1 | P21554 | 3/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10476227 | 1.00 | ALDH1A1 (0.40) | ALDH1A1LMNAHTTMEN1KMT2A | |
| SCHEMBL10476228 | 1.00 | ALDH1A1 (0.40) | ALDH1A1LMNAHTTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL507623 | 0.99 | ALDH1A1 (0.40) | ALDH1A1LMNAHTTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL507360 | 0.99 | ALDH1A1 (0.40) | ALDH1A1LMNAHTTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL507359 | 0.99 | ALDH1A1 (0.40) | ALDH1A1LMNAHTTMEN1KMT2A | |
| SCHEMBL10476270 | 0.89 | LMNA (0.52) | ALDH1A1LMNAHTTMEN1KMT2A | |
| SCHEMBL10476215 | 0.89 | LMNA (0.52) | ALDH1A1LMNAHTTMEN1KMT2A | |
| SCHEMBL10476213 | 0.89 | LMNA (0.52) | ALDH1A1LMNAHTTMEN1KMT2A | |
| SCHEMBL10277975 | 0.87 | KDM4E (0.37) | ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL10476202 | 0.87 | KDM4E (0.37) | ALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8580780-B2 | 6 substituted 2, 3,4,5 tetrahydro-1H-benzo[d]azepines as 5-HT2C receptor agonist | ELI LILLY AND COMPANY (US) | 2013-11-12 | — | — | US | claimed |
| EP-2479168-A1 | 6-Substituted 2,3,4,5-Tetrahydro-1H-Benzo [d]Azepines as 5-HT2C Receptor Agonists | ELI LILLY AND COMPANY (US) | 2012-07-25 | — | — | EP | claimed |