Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.82 |
| ▸ | CDC7 | O00311 | 1/20 | 0.74 |
| ▸ | PLK4 | O00444 | 1/20 | 0.74 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.74 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.74 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.74 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.74 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.74 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.74 |
| ▸ | CDK1 | P06493 | 1/20 | 0.74 |
| ▸ | CSF1R | P07333 | 1/20 | 0.74 |
| ▸ | PIM1 | P11309 | 1/20 | 0.74 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.74 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.74 |
| ▸ | CDK2 | P24941 | 1/20 | 0.74 |
| ▸ | TYK2 | P29597 | 1/20 | 0.74 |
| ▸ | AXL | P30530 | 1/20 | 0.74 |
| ▸ | FLT4 | P35916 | 1/20 | 0.74 |
| ▸ | KDR | P35968 | 1/20 | 0.74 |
| ▸ | FLT3 | P36888 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5594436 | 0.89 | MAPT (0.72) | MAPTCDC7PLK4CHEK1PDPK1 | |
| SCHEMBL12351294 | 0.83 | MAPT (0.83) | MAPTCDC7PLK4CHEK1PDPK1 | |
| SCHEMBL5594542 | 0.83 | MAPT (1.00) | MAPTCDC7PLK4CHEK1PDPK1 | |
| SCHEMBL10476363 | 0.81 | MEN1 (1.00) | MAPTCDC7PLK4CHEK1PDPK1 | |
| SCHEMBL14749136 | 0.78 | MAPT (0.76) | MAPTCDC7PLK4CHEK1PDPK1 | |
| SCHEMBL17799204 | 0.78 | MAPT (0.76) | MAPTCDC7PLK4CHEK1PDPK1 | |
| SCHEMBL17799202 | 0.78 | MAPT (0.76) | MAPTCDC7PLK4CHEK1PDPK1 | |
| SCHEMBL14476502 | 0.78 | MAPT (0.86) | MAPTCDC7PLK4CHEK1PDPK1 | |
| SCHEMBL27983596 | 0.78 | MAPT (0.78) | MAPTKMT2AMEN1POLBUSP2 | |
| SCHEMBL5594463 | 0.77 | MEN1 (0.67) | MAPTCDC7PLK4CHEK1PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778176-B1 | COMPOSITION FOR COLOURING KERATIN-CONTAINING FIBRES | HENKEL AG & CO KGAA (DE) | 2012-07-25 | — | — | EP | disclosed |