Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.79 |
| ▸ | MAPT | P10636 | 8/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.76 |
| ▸ | MEN1 | O00255 | 8/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.75 |
| ▸ | BLM | P54132 | 2/20 | 0.75 |
| ▸ | NSD2 | O96028 | 1/20 | 0.75 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 6/20 | 0.66 |
| ▸ | NPC1 | O15118 | 5/20 | 0.66 |
| ▸ | RAB9A | P51151 | 5/20 | 0.66 |
| ▸ | USP2 | O75604 | 2/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.65 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.65 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27983608 | 0.90 | MAPT (0.82) | THRBMAPTKDM4EMEN1KMT2A | |
| SCHEMBL12881142 | 0.86 | MEN1 (1.00) | THRBMAPTKDM4EMEN1KMT2A | |
| SCHEMBL5594708 | 0.86 | MEN1 (1.00) | THRBMAPTKDM4EMEN1KMT2A | |
| SCHEMBL5594463 | 0.83 | MEN1 (0.67) | THRBMAPTKDM4EMEN1KMT2A | |
| SCHEMBL10476383 | 0.82 | KMT2A (0.73) | THRBMAPTKDM4EMEN1KMT2A | |
| SCHEMBL10476385 | 0.82 | KMT2A (0.73) | THRBMAPTKDM4EMEN1KMT2A | |
| SCHEMBL10476363 | 0.80 | MEN1 (1.00) | THRBMAPTKDM4EMEN1KMT2A | |
| SCHEMBL13153929 | 0.80 | MEN1 (0.76) | THRBMAPTKDM4EMEN1KMT2A | |
| SCHEMBL12975925 | 0.80 | MEN1 (0.76) | THRBMAPTKDM4EMEN1KMT2A | |
| SCHEMBL12881130 | 0.80 | MEN1 (0.76) | THRBMAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778176-B1 | COMPOSITION FOR COLOURING KERATIN-CONTAINING FIBRES | HENKEL AG & CO KGAA (DE) | 2012-07-25 | — | — | EP | disclosed |