Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.82 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.82 |
| ▸ | THRB | P10828 | 1/20 | 0.80 |
| ▸ | MEN1 | O00255 | 8/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.76 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.76 |
| ▸ | NSD2 | O96028 | 1/20 | 0.72 |
| ▸ | BLM | P54132 | 1/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 6/20 | 0.66 |
| ▸ | USP2 | O75604 | 2/20 | 0.66 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.66 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.66 |
| ▸ | RECQL | P46063 | 1/20 | 0.66 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.66 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.66 |
| ▸ | NPC1 | O15118 | 6/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10476384 | 0.90 | THRB (0.79) | MAPTKDM4ETHRBMEN1KMT2A | |
| SCHEMBL5594708 | 0.84 | MEN1 (1.00) | MAPTKDM4ETHRBMEN1KMT2A | |
| SCHEMBL12881142 | 0.84 | MEN1 (1.00) | MAPTKDM4ETHRBMEN1KMT2A | |
| SCHEMBL10476383 | 0.83 | KMT2A (0.73) | MAPTKDM4ETHRBMEN1KMT2A | |
| SCHEMBL10476385 | 0.83 | KMT2A (0.73) | MAPTKDM4ETHRBMEN1KMT2A | |
| SCHEMBL27983596 | 0.83 | MAPT (0.78) | MAPTKDM4ETHRBMEN1KMT2A | |
| SCHEMBL5594404 | 0.81 | APP (0.64) | MAPTKDM4ETHRBMEN1KMT2A | |
| SCHEMBL12881130 | 0.81 | MEN1 (0.76) | MAPTKDM4ETHRBMEN1KMT2A | |
| SCHEMBL5594542 | 0.80 | MAPT (1.00) | MAPTKDM4ETHRBMEN1KMT2A | |
| SCHEMBL12351294 | 0.80 | MAPT (0.83) | MAPTKDM4ETHRBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104016973-B | A kind of method preparing two aromatic rings substituted olefines | 台州学院 | 2016-11-02 | — | — | CN | disclosed |
| CN-104016973-A | New method for preparing double-(hetero)aromatic-ring substituted alkene | UNIV TAIZHOU | 2014-09-03 | — | — | CN | disclosed |