Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 18/20 | 0.64 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4100070 | 0.89 | GPR119 (0.82) | GPR119 | |
| SCHEMBL4209310 | 0.88 | GPR119 (0.81) | GPR119DPP4DPP7 | |
| SCHEMBL10476590 | 0.88 | GPR119 (0.81) | GPR119DPP4DPP7 | |
| SCHEMBL10476561 | 0.85 | GPR119 (0.57) | GPR119DPP4DPP7 | |
| SCHEMBL4214372 | 0.84 | GPR119 (0.60) | GPR119DPP4DPP7 | |
| SCHEMBL10476642 | 0.84 | GPR119 (0.65) | GPR119 | |
| SCHEMBL14403646 | 0.84 | GPR119 (0.54) | GPR119 | |
| SCHEMBL4038491 | 0.81 | GPR119 (0.62) | GPR119 | |
| SCHEMBL10476598 | 0.81 | GPR119 (0.59) | GPR119 | |
| SCHEMBL4106094 | 0.79 | GPR119 (0.83) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2013201-B1 | HETEROCYCLIC GPCR AGONISTS | PROSIDION LTD (GB) | 2012-07-25 | — | — | EP | claimed |
| EP-2013201-B1 | HETEROCYCLIC GPCR AGONISTS | PROSIDION LTD (GB) | 2012-07-25 | — | — | EP | disclosed |