Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 17/20 | 0.62 |
| ▸ | NPY2R | P49146 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4107450 | 0.90 | GPR119 (0.77) | GPR119 | |
| SCHEMBL10476608 | 0.89 | GPR119 (0.49) | GPR119NPY2R | |
| SCHEMBL10476561 | 0.88 | GPR119 (0.57) | GPR119NPY2R | |
| SCHEMBL4209310 | 0.86 | GPR119 (0.81) | GPR119 | |
| SCHEMBL10476590 | 0.86 | GPR119 (0.81) | GPR119 | |
| SCHEMBL10476569 | 0.85 | GPR119 (0.61) | GPR119NPY2R | |
| SCHEMBL10476598 | 0.84 | GPR119 (0.59) | GPR119ALDH1A1NPSR1 | |
| SCHEMBL4100272 | 0.82 | GPR119 (0.52) | GPR119 | |
| SCHEMBL13696977 | 0.82 | GPR119 (0.48) | GPR119 | |
| SCHEMBL10476555 | 0.81 | GPR119 (0.64) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2013201-A1 | HETEROCYCLIC GPCR AGONISTS | Prosidion Limited (GB) | 2009-01-14 | — | — | EP | disclosed |
| WO-2007116229-A1 | HETEROCYCLIC GPCR AGONISTS | PROSIDION LIMITED (GB) | 2007-10-18 | — | — | WO | disclosed |