Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14840584 | 0.91 | TSHR (0.54) | TP53TSHRMAPK1ATMTDP1 | |
| SCHEMBL22868016 | 0.83 | ATM (0.47) | TP53TSHRMAPK1ATMTDP1 | |
| SCHEMBL14361867 | 0.82 | TP53 (0.59) | TP53TSHRMAPK1ATMTDP1 | |
| SCHEMBL23366711 | 0.81 | SLC6A3 (0.50) | TSHRMAPK1ATMTDP1L3MBTL1 | |
| SCHEMBL11480062 | 0.81 | DPP4 (0.61) | TSHRHTR2ADPP4F2TAAR1 | |
| SCHEMBL11478580 | 0.81 | DPP4 (0.61) | TSHRHTR2ADPP4F2TAAR1 | |
| Isopropylbenzene SCHEMBL7651427 | 0.80 | TP53 (0.56) | TP53TSHRMAPK1ATMTDP1 | |
| SCHEMBL444227 | 0.80 | TP53 (0.56) | TP53TSHRMAPK1ATMTDP1 | |
| SCHEMBL3634935 | 0.80 | TP53 (0.56) | TP53TSHRMAPK1ATMTDP1 | |
| SCHEMBL6546869 | 0.80 | TP53 (0.56) | TP53TSHRMAPK1ATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1070499-A | — | — | None | — | — | JP | disclosed |