Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | SFN | P31947 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9621662 | 0.85 | MAPT (0.83) | MAPTLMNAPOLBKMT2ANPC1 | |
| SCHEMBL9621389 | 0.83 | MAPT (0.68) | MAPTLMNAPOLBKMT2ANPC1 | |
| SCHEMBL9621048 | 0.81 | KMT2A (0.63) | MAPTLMNAPOLBKMT2ANPC1 | |
| SCHEMBL9621349 | 0.81 | MAPT (0.59) | MAPTLMNAPOLBKMT2ANPC1 | |
| SCHEMBL9621474 | 0.76 | KMT2A (0.56) | MAPTLMNAPOLBKMT2ANPC1 | |
| SCHEMBL11193309 | 0.76 | PLK1 (0.60) | MAPTLMNAPOLBKMT2ANPC1 | |
| SCHEMBL11144524 | 0.76 | KMT2A (0.58) | MAPTLMNAPOLBKMT2ANPC1 | |
| SCHEMBL11146960 | 0.76 | KMT2A (0.58) | MAPTLMNAPOLBKMT2ANPC1 | |
| SCHEMBL11146320 | 0.76 | MAPT (0.58) | MAPTLMNAPOLBKMT2ANPC1 | |
| SCHEMBL53437 | 0.75 | MAPT (0.60) | MAPTLMNAPOLBKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1139557-A | — | — | None | — | — | JP | disclosed |
| JP-H01139557-A | BENZAMIDE DERIVATIVE | HODOGAYA CHEM CO LTD | 1989-06-01 | — | — | JP | disclosed |