SCHEMBL10477309

SCHEMBL10477309

C=CC(=O)N(Cl)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 1/20 0.43
NPSR1 Q6W5P4 2/20 0.41
TRPM8 Q7Z2W7 2/20 0.40
ALDH1A1 P00352 3/20 0.39
RAB9A P51151 3/20 0.39
NPC1 O15118 2/20 0.39
POLB P06746 2/20 0.39
HTT P42858 2/20 0.39
KMT2A Q03164 1/20 0.39
TGM2 P21980 1/20 0.39
GLA P06280 2/20 0.35
TSHR P16473 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
BCL2A1 Q16548 1/20 0.35
ATM Q13315 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
MTNR1A P48039 1/20 0.34
MTNR1B P49286 1/20 0.34
PAX8 Q06710 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5580475 0.81 NPSR1 (0.43) NPSR1TRPM8ALDH1A1RAB9ANPC1
SCHEMBL1629579 0.78 TRPM8 (0.57) AKT1NPSR1TRPM8ALDH1A1RAB9A
SCHEMBL17591554 0.78 AKT1 (0.52) AKT1NPSR1TRPM8ALDH1A1RAB9A
SCHEMBL648421 0.77 AKT1 (0.45) AKT1NPSR1TRPM8ALDH1A1RAB9A
SCHEMBL4201822 0.76 NPSR1 (0.52) NPSR1TRPM8ALDH1A1RAB9ANPC1
SCHEMBL2724521 0.76 NPSR1 (0.46) NPSR1TRPM8ALDH1A1RAB9ANPC1
SCHEMBL8743210 0.75 AKT1 (0.48) AKT1NPSR1TRPM8ALDH1A1RAB9A
SCHEMBL6611167 0.75 AKT1 (0.43) AKT1NPSR1TRPM8ALDH1A1RAB9A
SCHEMBL7864460 0.75 NPSR1 (0.46) AKT1NPSR1TRPM8ALDH1A1RAB9A
SCHEMBL11883850 0.75 AKT1 (0.43) AKT1NPSR1TRPM8ALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4873166-A Liquid developer for electrophotography MITSUBISHI PAPER MILLS, LTD. (JP) 1989-10-10 US disclosed
US-3974238-A CROSSLINKED POLYBUTADIENE ACUSHNET COMPANY (US) 1976-08-10 US disclosed