Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11115139 | 0.90 | NPSR1 (0.56) | NPSR1ALDH1A1NPC1POLBHTT | |
| SCHEMBL560266 | 0.82 | NPSR1 (0.48) | NPSR1ALDH1A1NPC1POLBHTT | |
| SCHEMBL11073921 | 0.81 | NPSR1 (0.73) | NPSR1ALDH1A1NPC1POLBHTT | |
| SCHEMBL3730131 | 0.80 | NPSR1 (0.50) | NPSR1ALDH1A1NPC1POLBHTT | |
| SCHEMBL5932378 | 0.78 | NPSR1 (0.48) | NPSR1ALDH1A1NPC1POLBHTT | |
| SCHEMBL8380158 | 0.77 | POLB (0.52) | NPSR1ALDH1A1NPC1POLBHTT | |
| SCHEMBL20360661 | 0.77 | ALDH1A1 (0.55) | NPSR1ALDH1A1NPC1POLBHTT | |
| SCHEMBL5310808 | 0.77 | NPSR1 (0.43) | NPSR1ALDH1A1NPC1POLBHTT | |
| SCHEMBL16599595 | 0.77 | ALDH1A1 (0.55) | NPSR1ALDH1A1NPC1POLBHTT | |
| SCHEMBL6245249 | 0.76 | NPSR1 (0.46) | NPSR1ALDH1A1NPC1POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611109-A4 | NOVEL QUINAZOLINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMACEUTICAL CO LTD (JP) | 2009-06-24 | — | — | EP | claimed |
| JP-2006522109-A | — | — | 2006-09-28 | — | — | JP | claimed |
| EP-1611109-A1 | NOVEL QUINAZOLINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2006-01-04 | — | — | EP | claimed |
| WO-2004087680-A1 | NOVEL QUINAZOLINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2004-10-14 | — | — | WO | claimed |
| CN-115850123-B | Preparation method of 2, 4-dichloroaniline/hydrazine | 山东潍坊润丰化工股份有限公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-115850123-A | Preparation method of 2, 4-dichloroaniline/hydrazine | 山东潍坊润丰化工股份有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-113484436-B | Method for simultaneously determining content of five forbidden substances in bacteriostatic paper and application thereof | 云南中烟工业有限责任公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-113484436-A | Method for simultaneously determining content of five forbidden substances in bacteriostatic paper and application thereof | 云南中烟工业有限责任公司 | 2021-10-08 | — | — | CN | disclosed |
| CN-103121972-B | As the pyrimidine urea derivatives of kinase inhibitor | NOVARTIS AG (CH) | 2015-07-29 | — | — | CN | disclosed |
| CN-1283101-A | Improved antiperspirant activity and formulations made therefrom | COLGATE PALMOLIVE CO (US) | 2001-02-07 | — | — | CN | disclosed |
| EP-0060120-B1 | PROCESS FOR PREPARING 4-HALOAZETIDIN-2-ONES | ELI LILLY AND COMPANY (US) | 1984-12-19 | — | — | EP | disclosed |
| US-4368156-A | USING POSITIVE HALOGEN REAGENT | ELI LILLY AND COMPANY (US) | 1983-01-11 | — | — | US | disclosed |
| EP-0011370-B1 | PROCESS FOR PREPARING 2-CHLOROSULFINYL-AZETIDINONES | ELI LILLY AND COMPANY (US) | 1982-04-28 | — | — | EP | disclosed |
| US-4289695-A | REACTION OF A PHENICILLIN WITH AN N-CHLORO HALOGENATING AGENT IN PRESENCE OF A CROSSLINKED POLYVINYLPYRIDINE | ELI LILLY AND COMPANY (US) | 1981-09-15 | — | — | US | disclosed |
| EP-0011370-A1 | Process for preparing 2-chlorosulfinyl-azetidinones | ELI LILLY AND COMPANY (US) | 1980-05-28 | — | — | EP | disclosed |
| US-4165315-A | CHLORINATION WITH AN N-CHLORO HALOGENATING AGENT | ELI LILLY AND COMPANY (US) | 1979-08-21 | — | — | US | disclosed |
| US-4165316-A | Process for preparing sulfinyl chlorides from penicillin sulfoxides | ELI LILLY AND COMPANY (US) | 1979-08-21 | — | — | US | disclosed |
| US-4159272-A | Process for 2-chlorosulfinylazetidin-4-ones | ELI LILLY AND COMPANY (US) | 1979-06-26 | — | — | US | disclosed |
| US-4081440-A | Sulfinyl halides and their preparation from penicillin sulfoxides | ELI LILLY AND COMPANY (US) | 1978-03-28 | — | — | US | disclosed |
| US-4075203-A | Process for preparing a 3-exomethylenecepham sulfoxide from penicillin sulfoxides | ELI LILLY AND COMPANY (US) | 1978-02-21 | — | — | US | disclosed |