Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | PTPRB | P23467 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10477436 | 1.00 | HPGD (0.40) | HPGDCYP3A4KMT2AMEN1TSHR | |
| SCHEMBL10477418 | 0.89 | MEN1 (0.37) | HPGDCYP3A4KMT2AMEN1TSHR | |
| SCHEMBL10477415 | 0.89 | MEN1 (0.37) | HPGDCYP3A4KMT2AMEN1TSHR | |
| SCHEMBL10477390 | 0.88 | CYP3A4 (0.40) | HPGDCYP3A4KMT2AMEN1TSHR | |
| SCHEMBL10477364 | 0.87 | ALDH1A1 (0.37) | HPGDCYP3A4KMT2AMEN1TSHR | |
| SCHEMBL10477359 | 0.82 | MCL1 (0.39) | KMT2AMEN1MCL1ALDH1A1POLB | |
| SCHEMBL10477360 | 0.82 | MCL1 (0.39) | KMT2AMEN1MCL1ALDH1A1POLB | |
| SCHEMBL10477414 | 0.79 | MEN1 (0.45) | KMT2AMEN1MCL1ALDH1A1BACE1 | |
| SCHEMBL10477451 | 0.78 | EPHX1 (0.39) | HPGDKMT2AMEN1ALDH1A1HSD17B10 | |
| SCHEMBL16869910 | 0.77 | KMT2A (0.39) | CYP3A4KMT2AMEN1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4879398-A | Process for producing 2,6-disubstituted tyrosine | MONSANTO COMPANY (US) | 1989-11-07 | — | — | US | disclosed |