Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10477360 | 1.00 | MCL1 (0.39) | MCL1POLBKDM4EABL1MAPT | |
| SCHEMBL10477415 | 0.92 | MEN1 (0.37) | MCL1POLBKDM4EABL1MAPT | |
| SCHEMBL10477418 | 0.92 | MEN1 (0.37) | MCL1POLBKDM4EABL1MAPT | |
| SCHEMBL10477373 | 0.82 | HPGD (0.40) | MCL1POLBBACE1ALDH1A1KMT2A | |
| SCHEMBL10477436 | 0.82 | HPGD (0.40) | MCL1POLBBACE1ALDH1A1KMT2A | |
| SCHEMBL10477364 | 0.74 | ALDH1A1 (0.37) | MCL1KDM4EALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL10734451 | 0.73 | ALDH1A1 (0.52) | KDM4EMAPTBACE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10734447 | 0.73 | ALDH1A1 (0.52) | KDM4EMAPTBACE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28422488 | 0.73 | ALDH1A1 (0.52) | KDM4EMAPTBACE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8653628 | 0.71 | ALDH1A1 (0.58) | POLBKDM4EMAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4879398-A | Process for producing 2,6-disubstituted tyrosine | MONSANTO COMPANY (US) | 1989-11-07 | — | — | US | disclosed |