Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 5/20 | 0.32 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10477578 | 1.00 | NQO2 (0.33) | NQO2MTNR1AMTNR1BSTAT3FUCA1 | |
| SCHEMBL3575345 | 0.82 | NQO2 (0.35) | NQO2MTNR1AMTNR1BALDH1A1POLB | |
| SCHEMBL11414378 | 0.77 | DGAT2 (0.37) | STAT3 | |
| SCHEMBL11153114 | 0.77 | DGAT2 (0.37) | STAT3 | |
| SCHEMBL11313291 | 0.77 | DGAT2 (0.37) | STAT3 | |
| SCHEMBL11160918 | 0.77 | DGAT2 (0.37) | STAT3 | |
| SCHEMBL19852932 | 0.77 | DGAT2 (0.37) | STAT3 | |
| SCHEMBL11421254 | 0.77 | DGAT2 (0.37) | STAT3 | |
| SCHEMBL10040064 | 0.72 | STAT3 (0.36) | STAT3 | |
| SCHEMBL11420286 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4839346-A | Antitumor anthracycline glycosides, intermediates thereof, and composition and use thereof | FARMITALIA CARLO ERBA S.P.A. (IT) | 1989-06-13 | — | — | US | disclosed |