Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10477570 | 0.82 | NQO2 (0.33) | NQO2MTNR1AMTNR1BALDH1A1POLB | |
| SCHEMBL10477578 | 0.82 | NQO2 (0.33) | NQO2MTNR1AMTNR1BALDH1A1POLB | |
| SCHEMBL8612926 | 0.82 | MTNR1A (0.32) | MTNR1AMTNR1B | |
| SCHEMBL8622439 | 0.74 | TRPM8 (0.32) | — | |
| SCHEMBL7407325 | 0.72 | LGALS8 (0.34) | — | |
| SCHEMBL6438566 | 0.69 | MGAM (0.30) | — | |
| SCHEMBL10477571 | 0.69 | — | — | |
| SCHEMBL9404716 | 0.68 | NLRP3 (0.34) | — | |
| SCHEMBL3146279 | 0.67 | NQO2 (0.36) | NQO2MTNR1AMTNR1BALDH1A1POLB | |
| SCHEMBL27558257 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1391457-B1 | Substituted 2-Phenylbenzimidazoles and their use as PARP inhibitors | ABBVIE DEUTSCHLAND (DE) | 2013-12-25 | — | — | EP | disclosed |
| US-7781596-B1 | Substituted 2-phenylbenzimidazoles, the production thereof and their use | ABBOTT LABORATORIES (US) | 2010-08-24 | — | — | US | disclosed |
| EP-1127052-B1 | SUBSTITUTED 2-PHENYLBENZIMIDAZOLES, THE PRODUCTION THEREOF AND THEIR USE | ABBOTT GMBH & CO KG (DE) | 2004-12-08 | — | — | EP | disclosed |
| EP-1391457-A1 | Substituted 2-Phenylbenzimidazoles and their use as PARP inhibitors | Abbott GmbH & Co. KG (DE) | 2004-02-25 | — | — | EP | disclosed |
| US-6277850-B1 | EFFICIENCY, BIOCOMPATIBILITY, TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | ABBOTT LABORATORIES | 2001-08-21 | — | — | US | disclosed |
| EP-0906306-A1 | PYRROLYL QUINOXALINDIONES, THEIR PRODUCTION AND USE AS AMPA RECEPTOR ANTAGONISTS | BASF AKTIENGESELLSCHAFT (DE) | 1999-04-07 | — | — | EP | disclosed |
| US-5849744-A | Pyrrolyl tetrahydrobenzoquinoxaline diones, their preparation and use as glutamate receptor antagonist | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-15 | — | — | US | disclosed |
| US-5849743-A | Quinoxalines and drugs prepared therefrom | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-15 | — | — | US | disclosed |
| US-5773439-A | Amido-quinoxalinediones, the preparation and use thereof | BASF AKTIENGESELLSCHAFT (DE) | 1998-06-30 | — | — | US | disclosed |
| WO-1997049701-A1 | PYRROLYL QUINOXALINDIONES, THEIR PRODUCTION AND USE AS AMPA RECEPTOR ANTAGONISTS | BASF AKTIENGESELLSCHAFT (DE) | 1997-12-31 | — | — | WO | disclosed |
| CN-1152918-A | Novel amido quinoxaline diones, their preparation and use | BASF AG (DE) | 1997-06-25 | — | — | CN | disclosed |