Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 5/20 | 0.40 |
| ▸ | CA1 | P00915 | 5/20 | 0.40 |
| ▸ | CA2 | P00918 | 5/20 | 0.40 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9763623 | 0.82 | AR (0.38) | THRAARCA12CA1CA2 | |
| SCHEMBL10477735 | 0.81 | AR (0.40) | ARCA12CA1CA2CA4 | |
| SCHEMBL10488086 | 0.80 | AR (0.42) | ARCA12CA1CA2BCHE | |
| SCHEMBL9763301 | 0.78 | ADRB2 (0.37) | CA12CA1CA2CYP1A2CYP2D6 | |
| SCHEMBL9763657 | 0.76 | AR (0.38) | THRAARLIMK1LIMK2BCHE | |
| SCHEMBL10477931 | 0.74 | HPGD (0.50) | THRAARCA12CA1CA2 | |
| SCHEMBL10463959 | 0.72 | HPGD (0.50) | THRAARCA12CA1CA2 | |
| SCHEMBL10477677 | 0.72 | AR (0.52) | ARCA12CA1CA2CA4 | |
| SCHEMBL9763349 | 0.71 | ADRB2 (0.44) | CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL9762754 | 0.71 | LIMK2 (0.44) | LIMK1LIMK2CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4853381-A | Ethanolamine compounds | GLAXO GROUP LIMITED (GB) | 1989-08-01 | — | — | US | disclosed |