Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | C5AR1 | P21730 | 3/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11669905 | 0.81 | EGFR (0.43) | SMPD1 | |
| SCHEMBL10477737 | 0.80 | THRA (0.41) | ARCA12CA1CA2BCHE | |
| SCHEMBL9763623 | 0.79 | AR (0.38) | ARCA12CA1CA2 | |
| SCHEMBL10488546 | 0.77 | RAF1 (0.38) | SMPD1BCHE | |
| SCHEMBL10477735 | 0.77 | AR (0.40) | ARCA12CA1CA2 | |
| SCHEMBL9763301 | 0.76 | ADRB2 (0.37) | CA12CA1CA2 | |
| SCHEMBL456296 | 0.75 | FOLH1 (0.43) | — | |
| SCHEMBL11745909 | 0.75 | CYP19A1 (0.43) | ARSMPD1 | |
| SCHEMBL11671557 | 0.75 | EGFR (0.43) | SMPD1 | |
| Hydrochloric Acid SCHEMBL11670502 | 0.74 | EGFR (0.45) | ARSMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4853382-A | TREATING ASTHMA AND BRONCHITIS | GLAXO GROUP LIMITED (GB) | 1989-08-01 | — | — | US | disclosed |
| EP-0178919-B1 | AMINOPHENOL DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1988-12-21 | — | — | EP | disclosed |
| US-4730008-A | STIMULANT FOR BETA-ADRENORECEPTORS | GLAXO GROUP LIMITED (GB) | 1988-03-08 | — | — | US | disclosed |
| EP-0178919-A2 | Aminophenol derivatives | GLAXO GROUP LIMITED (GB) | 1986-04-23 | — | — | EP | disclosed |