Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | RRM1 | P23921 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7145799 | 1.00 | KMT2A (0.53) | KMT2AMEN1SMN1; SMN2RRM1MAOB | |
| SCHEMBL7488776 | 0.88 | SMN1; SMN2 (0.60) | KMT2AMEN1SMN1; SMN2MAOBLMNA | |
| SCHEMBL10477980 | 0.88 | KMT2A (0.50) | KMT2AMEN1SMN1; SMN2RRM1MAOB | |
| SCHEMBL322826 | 0.85 | LMNA (0.58) | SMN1; SMN2MAOBLMNACYP1A2PTGS1 | |
| SCHEMBL3923237 | 0.84 | KMT2A (0.53) | KMT2AMEN1SMN1; SMN2RRM1MAOB | |
| SCHEMBL13840614 | 0.84 | KMT2A (0.53) | KMT2AMEN1SMN1; SMN2RRM1MAOB | |
| SCHEMBL393316 | 0.84 | LMNA (0.56) | KMT2AMEN1MAOBLMNACYP1A2 | |
| SCHEMBL26563983 | 0.83 | KMT2A (0.59) | KMT2AMEN1SMN1; SMN2RRM1MAOB | |
| SCHEMBL10926521 | 0.81 | KMT2A (0.53) | KMT2AMEN1SMN1; SMN2MAOBLMNA | |
| SCHEMBL31185833 | 0.80 | RRM1 (0.57) | KMT2AMEN1SMN1; SMN2RRM1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4853381-A | Ethanolamine compounds | GLAXO GROUP LIMITED (GB) | 1989-08-01 | — | — | US | disclosed |
| EP-0162576-B1 | ETHANOLAMINE COMPOUNDS | GLAXO GROUP LIMITED (GB) | 1989-07-26 | — | — | EP | disclosed |
| EP-0223410-A2 | Ethanolamine Derivatives | GLAXO GROUP LIMITED (GB) | 1987-05-27 | — | — | EP | disclosed |
| EP-0162576-A1 | Ethanolamine compounds | GLAXO GROUP LIMITED (GB) | 1985-11-27 | — | — | EP | disclosed |