Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | AKT2 | P31751 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | COMT | P21964 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10478397 | 0.81 | OPRM1 (0.51) | OPRM1SLC6A4DRD2SIGMAR1CYP1A2 | |
| SCHEMBL10620938 | 0.81 | OPRM1 (0.53) | OPRM1HTR2AAKT2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10478268 | 0.80 | OPRM1 (0.50) | OPRM1SLC6A4DRD2SIGMAR1CYP1A2 | |
| Hydrochloric Acid SCHEMBL10478033 | 0.80 | OPRM1 (0.51) | OPRM1HTR2AAKT2MEN1KMT2A | |
| SCHEMBL10478400 | 0.79 | OPRM1 (0.50) | OPRM1HTR2ASLC6A4AKT2MEN1 | |
| SCHEMBL738518 | 0.73 | OPRM1 (1.00) | OPRM1HTR2ASLC6A4SLC6A2AKT2 | |
| Hydrochloric Acid SCHEMBL20292111 | 0.71 | SLC6A2 (0.42) | SLC6A4SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL1765284 | 0.71 | OPRM1 (0.95) | OPRM1HTR2ASLC6A4SLC6A2AKT2 | |
| Oxalic Acid SCHEMBL10478290 | 0.71 | OPRM1 (0.40) | OPRM1HTR2AAKT2PTGDR2KCNH2 | |
| SCHEMBL4631246 | 0.69 | OPRM1 (0.56) | OPRM1HTR2ASLC6A4SLC6A2AKT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4845095-A | ANALGESICS, NEUROLEPTICS | A/S FERROSAN (DK) | 1989-07-04 | — | — | US | disclosed |
| EP-0285032-A1 | 4-Phenylpiperidine compounds and their preparation and use | A/S FERROSAN (DK) | 1988-10-05 | — | — | EP | disclosed |