Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | S100B | P04271 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | ADK | P55263 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6252567 | 0.80 | ALDH1A1 (0.48) | APAF1SLC2A1ALDH1A1CYP3A4MAPK1 | |
| SCHEMBL9658441 | 0.79 | TSHR (0.49) | APAF1SLC2A1ALDH1A1CYP3A4MAPK1 | |
| SCHEMBL8130850 | 0.79 | CYP3A4 (0.43) | ALDH1A1CYP3A4MAPK1TDP1TSHR | |
| SCHEMBL5921994 | 0.79 | SLC2A1 (0.47) | APAF1SLC2A1ALDH1A1CYP3A4MAPK1 | |
| SCHEMBL5011910 | 0.77 | ALDH1A1 (0.48) | APAF1SLC2A1ALDH1A1CYP3A4MAPK1 | |
| SCHEMBL5011906 | 0.77 | ALDH1A1 (0.48) | APAF1SLC2A1ALDH1A1CYP3A4MAPK1 | |
| SCHEMBL6739605 | 0.76 | ALDH1A1 (0.70) | APAF1ALDH1A1CYP3A4MAPK1TDP1 | |
| SCHEMBL5009553 | 0.75 | SLC2A1 (0.47) | APAF1SLC2A1ALDH1A1CYP3A4MAPK1 | |
| SCHEMBL5009555 | 0.75 | SLC2A1 (0.47) | APAF1SLC2A1ALDH1A1CYP3A4MAPK1 | |
| SCHEMBL10478219 | 0.75 | SLC2A1 (0.38) | SLC2A1ALDH1A1CYP3A4MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4818660-A | POLYMERIC BINDER AND UNSATURATED COMPOUND, PHOTOINITIATOR, BAS IC DYE, LEUCO DYE AND STRONG ACID | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-04-04 | — | — | US | disclosed |
| EP-0115198-B1 | ELECTROPHOTOGRAPHIC PHOTOCONDUCTIVE ELEMENTS | TOMOEGAWA PAPER MANUFACTURING COMPANY LIMITED (JP) | 1987-03-11 | — | — | EP | disclosed |
| US-4539282-A | SENSITIZED ZINC OXIDE, POLYCARBONATE BINDER AND AROMATIC DIAMINE | TOMOEGAWA PAPER MANUFACTURING COMPANY LIMITED (JP) | 1985-09-03 | — | — | US | disclosed |
| EP-0115198-A1 | Electrophotographic photoconductive elements | TOMOEGAWA PAPER MANUFACTURING COMPANY LIMITED (JP) | 1984-08-08 | — | — | EP | disclosed |