SCHEMBL5011906

SCHEMBL5011906

Cc1cc(N(C)C)ccc1C(c1ccc(N)cc1)c1ccc(N(C)C)cc1C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.48
CYP3A4 P08684 3/20 0.48
MAPK1 P28482 3/20 0.48
TDP1 Q9NUW8 3/20 0.48
ALOX15 P16050 2/20 0.48
TP53 P04637 2/20 0.48
SLC2A1 P11166 1/20 0.39
APAF1 O14727 1/20 0.37
MAPT P10636 3/20 0.37
TSHR P16473 4/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
CYP1A2 P05177 1/20 0.36
PHLPP2 Q6ZVD8 1/20 0.36
GAA P10253 2/20 0.34
PKM P14618 1/20 0.34
HTT P42858 1/20 0.34
MCL1 Q07820 1/20 0.34
PSMD14 O00487 1/20 0.32
RECQL P46063 1/20 0.32
GFER P55789 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6252567 0.90 ALDH1A1 (0.48) ALDH1A1CYP3A4MAPK1TDP1ALOX15
SCHEMBL5921994 0.90 SLC2A1 (0.47) ALDH1A1CYP3A4MAPK1TDP1ALOX15
SCHEMBL5011910 0.87 ALDH1A1 (0.48) ALDH1A1CYP3A4MAPK1TDP1ALOX15
SCHEMBL5009553 0.86 SLC2A1 (0.47) ALDH1A1CYP3A4MAPK1TDP1ALOX15
SCHEMBL11331423 0.83 APP (0.41) ALDH1A1CYP3A4MAPK1TDP1TP53
SCHEMBL75642 0.83 MAPT (0.41) ALDH1A1CYP3A4MAPK1TDP1ALOX15
SCHEMBL13792150 0.83 S100B (0.54) ALDH1A1CYP3A4MAPK1TDP1TP53
SCHEMBL3193700 0.82 MAPT (0.46) ALDH1A1CYP3A4MAPK1TDP1ALOX15
SCHEMBL38662618 0.82 MAPT (0.46) ALDH1A1CYP3A4MAPK1TDP1ALOX15
SCHEMBL10478215 0.81 SLC2A1 (0.65) ALDH1A1MAPK1TDP1TP53SLC2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080311524-A1 Method For Making Negative-Working Heat-Sensitive Lithographic Printing Plate Precursor AGFA GRAPHICS N.V. (BE) 2008-12-18 US disclosed
US-20060078802-A1 Holographic storage medium SABIC INNOVATIVE PLASTICS IP B.V. 2006-04-13 US disclosed
EP-0239868-B1 PHOTOCHROMIC SYSTEM, LAYER PREPARED THEREOF AND ITS USE BASF Aktiengesellschaft (DE) 1989-12-27 EP disclosed
US-4857438-A Photochromic system and layers produced therewith BASF AKTIENGESELLSCHAFT (DE) 1989-08-15 US disclosed
EP-0239868-A1 Photochromic system, layer prepared thereof and its use BASF Aktiengesellschaft (DE) 1987-10-07 EP disclosed
US-4332884-A USING A DIOXIME CHELATING AGENT RICOH CO., LTD. (JP) 1982-06-01 US disclosed
US-4306014-A AMMONIA OR AMINES SUPPRESS THE COLOR-FORMING REACTION SYSTEM RICOH CO., LTD. (JP) 1981-12-15 US disclosed
US-4251619-A Process for forming photo-polymeric image KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-02-17 US disclosed