Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GART | P22102 | 7/20 | 0.57 |
| ▸ | ATIC | P31939 | 3/20 | 0.49 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.46 |
| ▸ | MTHFD2 | P13995 | 2/20 | 0.45 |
| ▸ | MTHFD1 | P11586 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10479205 | 1.00 | GART (0.57) | GARTATICSOSTMTHFD2MTHFD1 | |
| SCHEMBL10479169 | 1.00 | GART (0.57) | GARTATICSOSTMTHFD2MTHFD1 | |
| SCHEMBL10479203 | 1.00 | GART (0.57) | GARTATICSOSTMTHFD2MTHFD1 | |
| SCHEMBL10479154 | 1.00 | GART (0.57) | GARTATICSOSTMTHFD2MTHFD1 | |
| SCHEMBL9536040 | 0.93 | GART (0.56) | GARTATIC | |
| SCHEMBL9534949 | 0.90 | GART (0.58) | GARTATICSOSTMTHFD2MTHFD1 | |
| SCHEMBL9536050 | 0.88 | GART (0.50) | GARTATIC | |
| SCHEMBL9263123 | 0.86 | GART (0.63) | GARTATIC | |
| SCHEMBL9446048 | 0.86 | GART (0.61) | GARTATICSOSTMTHFD1 | |
| SCHEMBL9536834 | 0.86 | GART (0.57) | GARTATIC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4883799-A | N-(4-(1-hydroxy-3-(5,6,7,8-tetrahydropyrido(2,3,-d)-pyrimidin-6-yl)prop-2-yl)benzoyl)glutamic acid derivatives | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1989-11-28 | — | — | US | claimed |
| US-4883799-A | N-(4-(1-hydroxy-3-(5,6,7,8-tetrahydropyrido(2,3,-d)-pyrimidin-6-yl)prop-2-yl)benzoyl)glutamic acid derivatives | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1989-11-28 | — | — | US | disclosed |
| US-4883799-A | N-(4-(1-hydroxy-3-(5,6,7,8-tetrahydropyrido(2,3,-d)-pyrimidin-6-yl)prop-2-yl)benzoyl)glutamic acid derivatives | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1989-11-28 | — | — | US | disclosed |