Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.74 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 4/20 | 0.48 |
| ▸ | CYP2J2 | P51589 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10479207 | 0.94 | P2RX7 (0.65) | P2RX7KCNH2HRH1MEN1 | |
| SCHEMBL10479186 | 0.91 | P2RX7 (0.62) | P2RX7KCNH2CHRM1DRD2HRH1 | |
| SCHEMBL10479180 | 0.86 | P2RX7 (0.57) | P2RX7KCNH2CHRM1DRD2HRH1 | |
| SCHEMBL10731970 | 0.79 | P2RX7 (0.67) | P2RX7KCNH2DRD2HRH1MEN1 | |
| SCHEMBL10732158 | 0.79 | P2RX7 (0.88) | P2RX7KCNH2CHRM1HRH1 | |
| SCHEMBL10731801 | 0.78 | P2RX7 (0.85) | P2RX7KCNH2CHRM1DRD2HRH1 | |
| SCHEMBL10734439 | 0.78 | P2RX7 (0.71) | P2RX7KCNH2CHRM1MEN1 | |
| SCHEMBL10731808 | 0.78 | P2RX7 (0.77) | P2RX7KCNH2DRD2HRH1CYP2J2 | |
| SCHEMBL10479163 | 0.76 | P2RX7 (0.48) | P2RX7KCNH2HRH1CYP2J2 | |
| SCHEMBL7656612 | 0.76 | P2RX7 (0.74) | P2RX7KCNH2DRD2HRH1CYP2J2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4806560-A | ANTIHISTAMINES AND ANTISEROTONINE AGENTS | SYNTHELABO (FR) | 1989-02-21 | — | — | US | disclosed |