Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.67 |
| ▸ | ACHE | P22303 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.58 |
| ▸ | SLC18A2 | Q05940 | 2/20 | 0.58 |
| ▸ | DRD2 | P14416 | 2/20 | 0.58 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.58 |
| ▸ | DRD3 | P35462 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.58 |
| ▸ | DRD1 | P21728 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10732158 | 0.87 | P2RX7 (0.88) | P2RX7HPGDLMNAKCNH2DRD3 | |
| SCHEMBL10479207 | 0.85 | P2RX7 (0.65) | P2RX7KCNH2MEN1HTR7HRH1 | |
| SCHEMBL10479161 | 0.79 | P2RX7 (0.74) | P2RX7KCNH2DRD2MEN1HRH1 | |
| SCHEMBL13904312 | 0.78 | ACHE (0.58) | ACHEALDH1A1HPGDCYP3A4CYP2C19 | |
| SCHEMBL10734439 | 0.77 | P2RX7 (0.71) | P2RX7HPGDLMNAKCNH2DRD3 | |
| SCHEMBL7656612 | 0.77 | P2RX7 (0.74) | P2RX7LMNAKCNH2DRD2DRD3 | |
| SCHEMBL10731808 | 0.77 | P2RX7 (0.77) | P2RX7LMNAKCNH2DRD2DRD3 | |
| SCHEMBL13944264 | 0.77 | HTR2A (0.83) | ACHEALDH1A1HPGDCYP3A4CYP2C19 | |
| SCHEMBL17474575 | 0.76 | SLC18A2 (0.72) | ALDH1A1HPGDCYP3A4CYP2C19LMNA | |
| SCHEMBL11007868 | 0.76 | ADRA1D (0.61) | ALDH1A1HPGDCYP3A4CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4680296-A | ANTIALLERGENS, ANTIPRUITIC AGENTS | SYNTHELABO (FR) | 1987-07-14 | — | — | US | disclosed |