Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.37 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.37 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.37 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 5/20 | 0.37 |
| ▸ | CA9 | Q16790 | 5/20 | 0.37 |
| ▸ | DUT | P33316 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10479183 | 0.95 | LMNA (0.40) | LMNAKMT2ASMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL10479252 | 0.92 | LMNA (0.44) | LMNAKMT2ASMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL11399957 | 0.83 | SMN1; SMN2 (0.52) | LMNAKMT2ASMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL11397970 | 0.82 | SMN1; SMN2 (0.51) | LMNAKMT2ASMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL13650209 | 0.81 | LMNA (0.50) | LMNAKMT2ASMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL5017332 | 0.79 | LMNA (0.49) | LMNAKMT2ASMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL3786418 | 0.78 | UPP1 (0.57) | LMNAKMT2AKDM4ECYP1A2GRIA1 | |
| SCHEMBL5015576 | 0.77 | LMNA (0.48) | LMNAKMT2ASMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL9596932 | 0.77 | DUT (0.63) | LMNAKMT2ASMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL6372044 | 0.77 | LMNA (0.56) | LMNAKMT2ASMN1; SMN2KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4868189-A | ANTICANCER AGENTS | SANWA KAGAKU KENKYUSHO CO. (JP) | 1989-09-19 | — | — | US | claimed |
| EP-0280841-A2 | Organo-silicone compounds and use thereof | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1988-09-07 | — | — | EP | claimed |
| US-4868189-A | ANTICANCER AGENTS | SANWA KAGAKU KENKYUSHO CO. (JP) | 1989-09-19 | — | — | US | disclosed |
| EP-0280841-A2 | Organo-silicone compounds and use thereof | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1988-09-07 | — | — | EP | disclosed |