Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | UGCG | Q16739 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RPA1 | P27694 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5812502 | 0.97 | PTGS2 (0.59) | PTGS2PTGS1CYP1A2HIF1AGRIA2 | |
| SCHEMBL20604173 | 0.86 | PTGS2 (0.60) | PTGS2PTGS1CYP1A2GRIA2CYP2C9 | |
| SCHEMBL10479480 | 0.85 | GRIA2 (0.46) | PTGS2PTGS1CYP1A2GRIA2CYP2C9 | |
| SCHEMBL14662754 | 0.83 | PTGS2 (0.60) | PTGS2PTGS1CYP1A2GRIA2CYP2C9 | |
| SCHEMBL10479738 | 0.82 | GRIA2 (0.46) | PTGS2PTGS1CYP1A2GRIA2CYP2C9 | |
| SCHEMBL25434903 | 0.82 | TP53 (0.55) | PTGS2PTGS1UGCGFABP4RPA1 | |
| SCHEMBL5811399 | 0.82 | CNR1 (0.65) | PTGS2UGCGCNR1CNR2RPA1 | |
| SCHEMBL10479510 | 0.81 | KDM4E (0.49) | PTGS2CYP1A2GRIA2CYP2C9GAA | |
| SCHEMBL10479625 | 0.80 | KMT2A (0.54) | PTGS2PTGS1SMN1; SMN2 | |
| SCHEMBL10479406 | 0.79 | PTGS2 (0.58) | PTGS2PTGS1CYP1A2GRIA2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4851425-A | Cyclopentapyrazole and tetrahydroindazole compounds and their use as anti-inflammatory and anti-allergic agents | THE UPJOHN COMPANY (US) | 1989-07-25 | — | — | US | disclosed |