Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | OXTR | P30559 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10480597 | 0.78 | BCAT2 (0.58) | BCAT2SMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL4027665 | 0.78 | MEN1 (0.79) | BCAT2SMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL10480572 | 0.75 | BCAT2 (0.58) | BCAT2SMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL2774997 | 0.74 | SLC6A2 (0.49) | SMN1; SMN2TSHRMEN1KMT2ARAB9A | |
| SCHEMBL28425403 | 0.72 | BCAT2 (0.59) | BCAT2SMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL1339580 | 0.72 | ALDH1A1 (0.48) | SMN1; SMN2TSHRMEN1KMT2ASLC6A2 | |
| SCHEMBL25344922 | 0.71 | BCAT2 (0.53) | BCAT2SMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL4028874 | 0.71 | BCAT2 (0.53) | BCAT2SMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL4020558 | 0.71 | BCAT2 (0.53) | BCAT2SMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL30661081 | 0.70 | BCAT2 (1.00) | BCAT2SMN1; SMN2TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1989001478-A1 | ARYLOXY- AND ARALKYLTHIO-IMIDAZO[1,2-b]PYRIDAZINES | THE AUSTRALIAN NATIONAL UNIVERSITY (AU) | 1989-02-23 | — | — | WO | disclosed |