SCHEMBL1048071

SCHEMBL1048071

Clc1ccc(-c2nc(C(Br)(Br)Br)nc(C(Br)(Br)Br)n2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.52
RAB9A P51151 5/20 0.52
RPA1 P27694 1/20 0.39
MEN1 O00255 4/20 0.39
KMT2A Q03164 4/20 0.39
ADORA3 P0DMS8 2/20 0.39
NPSR1 Q6W5P4 1/20 0.39
RXFP1 Q9HBX9 1/20 0.39
AHR P35869 1/20 0.39
NOTUM Q6P988 2/20 0.38
NR1H4 Q96RI1 1/20 0.38
MAPT P10636 1/20 0.38
NR1H2 P55055 1/20 0.38
NR1H3 Q13133 1/20 0.38
SIRT2 Q8IXJ6 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
CASP3 P42574 2/20 0.37
DHFR P00374 1/20 0.37
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL80044 0.83 NPC1 (0.52) NPC1RAB9ARPA1MEN1KMT2A
SCHEMBL125517 0.81 NPC1 (0.50) NPC1RAB9ARPA1MEN1KMT2A
SCHEMBL9849727 0.80 NR1H4 (0.41) NPC1RAB9AMEN1KMT2AAHR
SCHEMBL9849715 0.78 CYP1A2 (0.40) NPC1RAB9AMEN1KMT2AADORA3
SCHEMBL9869365 0.78 NPC1 (0.68) NPC1RAB9ARPA1MEN1KMT2A
SCHEMBL1043823 0.77 ADORA2A (0.48) NPC1RAB9AMEN1KMT2AADORA3
SCHEMBL1049369 0.76 IDO1 (0.46) NPC1RAB9ANOTUMMAPTSMN1; SMN2
SCHEMBL17269507 0.76 NPC1 (0.65) NPC1RAB9ARPA1MEN1KMT2A
SCHEMBL14374410 0.76 NPC1 (0.65) NPC1RAB9ARPA1MEN1KMT2A
SCHEMBL9622217 0.74 ADORA3 (0.42) NPC1RAB9AADORA3SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0621508-B1 Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO LTD (JP) 1996-09-25 EP claimed
US-5494777-A Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1996-02-27 US claimed
EP-0621508-A1 Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1994-10-26 EP claimed
EP-0137228-B1 PHOTOPOLYMERIZABLE COMPOSITION FUJI PHOTO FILM CO., LTD. (JP) 1988-10-05 EP claimed
EP-0137228-A2 Photopolymerizable composition FUJI PHOTO FILM CO., LTD. (JP) 1985-04-17 EP claimed
US-11746255-B2 Hard-mask composition IRRESISTIBLE MATERIALS LTD (GB) 2023-09-05 US disclosed
CN-109562944-B Hard mask composition 亚历克斯·菲利普·格雷厄姆·罗宾逊 2022-09-09 CN disclosed
CN-112119133-B Hard mask composition 亚历克斯·P·G·罗宾逊 2022-05-24 CN disclosed
US-10438808-B2 Hard-mask composition IRRESISTIBLE MATERIALS, LTD (GB) 2019-10-08 US disclosed
US-10290500-B2 Spin on hard mask material IRRESISTIBLE MATERIALS LTD (GB) 2019-05-14 US disclosed
US-20190127604-A1 HARD-MASK COMPOSITION NANO-C, INC. 2019-05-02 US disclosed
US-20170345669-A1 HARD-MASK COMPOSITION NANO-C, INC. 2017-11-30 US disclosed
US-5609988-A NEGATIVE RESIST, NOVOLAK, METHYLOL OR METHOXYMETHYL CURING AGENT, 2-BENZODIOXOLYL-4,6-BIS(TRICHLOROMETHYL)TRIAZINE ACID GENERATING AGENT JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1997-03-11 US disclosed
EP-0621508-B1 Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO LTD (JP) 1996-09-25 EP disclosed
EP-0621509-A1 Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1994-10-26 EP disclosed
EP-0621508-A1 Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1994-10-26 EP disclosed
US-5030548-A Photoiniator system comprising a 4,4'-bis(dialkylamino) benzophenone, an aromatic ketone and lophine dimer; also present a halogen compound leuco and dye; lithography; printing plates; photoresists FUJI PHOTO FILM CO., LTD. (JP) 1991-07-09 US disclosed
US-4661434-A PHOTORESISTS FUJI PHOTO FILM CO., LTD. (JP) 1987-04-28 US disclosed
US-4657942-A LITHOGRAPHIC PRINTING PLATES, RESIN LETTERPRESS, RESISTS, 2-MERCAPTO-1,3,4-TIADIAZOLE FOR INCREASED SENSITIVITY FUJI PHOTO FILM CO., LTD. (JP) 1987-04-14 US disclosed
EP-0137228-A2 Photopolymerizable composition FUJI PHOTO FILM CO., LTD. (JP) 1985-04-17 EP disclosed