Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.65 |
| ▸ | THPO | P40225 | 1/20 | 0.65 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.58 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Imidazole SCHEMBL10480985 | 0.91 | MEN1 (0.63) | NR3C2MAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL6455316 | 0.89 | MAPT (0.80) | NR3C2MAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL336400 | 0.89 | MAPT (0.80) | NR3C2MAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4654952 | 0.89 | MAPT (0.80) | NR3C2MAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7384519 | 0.89 | MAPT (0.80) | NR3C2MAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4654954 | 0.89 | MAPT (0.80) | NR3C2MAPTCYP1A2CYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL6234505 | 0.88 | MAPT (0.78) | NR3C2MAPTCYP1A2CYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL10464261 | 0.88 | MAPT (0.78) | NR3C2MAPTCYP1A2CYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL4661058 | 0.88 | MAPT (0.78) | NR3C2MAPTCYP1A2CYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL10464259 | 0.88 | MAPT (0.78) | NR3C2MAPTCYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4798840-A | Coronary-active fluorine-containing 1,4-dihydropyridines | BAYER AKTIENGESELLSCHAFT (DE) | 1989-01-17 | — | — | US | disclosed |