Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.63 |
| ▸ | THPO | P40225 | 2/20 | 0.63 |
| ▸ | CACNA1C | Q13936 | 5/20 | 0.59 |
| ▸ | CACNA1F | O60840 | 4/20 | 0.59 |
| ▸ | CACNA1D | Q01668 | 4/20 | 0.59 |
| ▸ | CACNA1S | Q13698 | 4/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.58 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.58 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Imidazole SCHEMBL10480974 | 0.91 | NR3C2 (0.67) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7266605 | 0.90 | MEN1 (0.76) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7272138 | 0.90 | MEN1 (0.76) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7421240 | 0.90 | MEN1 (0.76) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL7300438 | 0.89 | MEN1 (0.74) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11011759 | 0.86 | MEN1 (0.82) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11690705 | 0.83 | MEN1 (0.69) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL28612902 | 0.82 | MEN1 (0.76) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7159699 | 0.82 | ADORA3 (0.81) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL30357961 | 0.82 | ADORA3 (0.81) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4798840-A | Coronary-active fluorine-containing 1,4-dihydropyridines | BAYER AKTIENGESELLSCHAFT (DE) | 1989-01-17 | — | — | US | disclosed |