Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18935418 | 1.00 | SMN1; SMN2 (0.56) | SMN1; SMN2MEN1KMT2AHDAC8HDAC6 | |
| SCHEMBL24997854 | 1.00 | SMN1; SMN2 (0.56) | SMN1; SMN2MEN1KMT2AHDAC8HDAC6 | |
| SCHEMBL18935499 | 1.00 | SMN1; SMN2 (0.56) | SMN1; SMN2MEN1KMT2AHDAC8HDAC6 | |
| SCHEMBL24997802 | 1.00 | SMN1; SMN2 (0.56) | SMN1; SMN2MEN1KMT2AHDAC8HDAC6 | |
| SCHEMBL1940413 | 0.98 | SMN1; SMN2 (0.55) | SMN1; SMN2MEN1KMT2AHDAC8HDAC6 | |
| Hydrochloric Acid SCHEMBL573477 | 0.98 | SMN1; SMN2 (0.55) | SMN1; SMN2MEN1KMT2AHDAC8HDAC6 | |
| SCHEMBL1703385 | 0.98 | SMN1; SMN2 (0.58) | SMN1; SMN2MEN1KMT2AHDAC8HDAC6 | |
| SCHEMBL12375164 | 0.93 | SMN1; SMN2 (0.58) | SMN1; SMN2MEN1KMT2AHDAC8HDAC6 | |
| SCHEMBL172134 | 0.90 | — | — | |
| SCHEMBL10076786 | 0.90 | SMN1; SMN2 (0.60) | SMN1; SMN2MEN1KMT2AHDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 262 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024099402-A1 | INTERMEDIATES AND PROCESS OF COMPOUNDS FOR THE DEGRADATION OF EGFR KINASE | BEIGENE (BEIJING) CO., LTD. (CN) | 2024-05-16 | — | — | WO | claimed |
| EP-3027604-A2 | NOVEL QUINAZOLINONES AS BROMODOMAIN INHIBITORS | Zenith Epigenetics Corp. (CA) | 2016-06-08 | — | — | EP | claimed |
| WO-1995024404-A1 | PREPARATION OF SYMMETRICAL AND UNSYMMETRICAL DITHIIN COMPOUNDS | SHAMAN PHARMACEUTICALS, INC. (US) | 1995-09-14 | — | — | WO | claimed |
| US-12036209-B2 | Compounds and methods for the targeted degradation of Interleukin-1 receptor-associated kinase 4 polypeptides | ARVINAS OPERATIONS, INC. (US) | 2024-07-16 | — | — | US | disclosed |
| US-20240208968-A1 | ALPHA V BETA 6 AND ALPHA V BETA 1 INTEGRIN INHIBITORS AND USES THEREOF | DICE MOLECULES SV, INC. | 2024-06-27 | — | — | US | disclosed |
| WO-2024099402-A1 | INTERMEDIATES AND PROCESS OF COMPOUNDS FOR THE DEGRADATION OF EGFR KINASE | BEIGENE (BEIJING) CO., LTD. (CN) | 2024-05-16 | — | — | WO | disclosed |
| WO-2024064363-A2 | LIGNIN-BASED BIODEGRADABLE POLYMERS AND METHODS OF MAKING THE SAME | The Florida State University Research Foundation, Inc. (US) | 2024-03-28 | — | — | WO | disclosed |
| WO-2024064361-A1 | LIGNIN-BASED BIODEGRADABLE POLYMERS AND METHODS OF MAKING THE SAME | The Florida State University Research Foundation, Inc. (US) | 2024-03-28 | — | — | WO | disclosed |
| US-11857519-B2 | Compounds and methods for the targeted degradation of enhancer of zeste homolog 2 polypeptide | ARVINAS OPERATIONS, INC. (US) | 2024-01-02 | — | — | US | disclosed |
| US-20230353959-A1 | PI3K-ALPHA INHIBITORS AND METHODS OF USE THEREOF | RELAY THERAPEUTICS, INC. | 2023-11-02 | — | — | US | disclosed |
| US-20230353959-A1 | PI3K-ALPHA INHIBITORS AND METHODS OF USE THEREOF | RELAY THERAPEUTICS, INC. | 2023-11-02 | — | — | US | disclosed |
| US-5587393-A | ANGIOTENSIN ANTAGONIST USEFUL IN TREATING HYPERTENSION | DR. KARL THOMAE GMBH (DE) | 1996-12-24 | — | — | US | disclosed |
| WO-1995024404-A1 | PREPARATION OF SYMMETRICAL AND UNSYMMETRICAL DITHIIN COMPOUNDS | SHAMAN PHARMACEUTICALS, INC. (US) | 1995-09-14 | — | — | WO | disclosed |
| US-5385925-A | Benzimidazoles, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1995-01-31 | — | — | US | disclosed |
| WO-1991014689-A1 | ANTIMALARIAL ANALOGS OF ARTEMISININ | SRI INTERNATIONAL (US) | 1991-10-03 | — | — | WO | disclosed |
| EP-0229007-B1 | ANTICONVULSANT GAMMA-THIOBUTYROLACTONE DERIVATIVES | WASHINGTON UNIVERSITY (US) | 1990-11-28 | — | — | EP | disclosed |
| US-4707491-A | Anticonvulsant γ-thiobutyrolactone derivatives | WASHINGTON UNIVERSITY (US) | 1987-11-17 | — | — | US | disclosed |
| EP-0229007-A1 | Anticonvulsant gamma-thiobutyrolactone derivatives | WASHINGTON UNIVERSITY (US) | 1987-07-15 | — | — | EP | disclosed |
| EP-0188185-A1 | Novel n-acyl-isopropylglycine derivatives | Monsanto Company (US) | 1986-07-23 | — | — | EP | disclosed |
| EP-0027020-A1 | 2-Substituted-4-alkyl or trihaloalkyl-5-oxazolecarboxylic acid derivatives, their use as safening agents and herbicidal compositions containing them | MONSANTO COMPANY (US) | 1981-04-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240208968-A1 | ALPHA V BETA 6 AND ALPHA V BETA 1 INTEGRIN INHIBITORS AND USES THEREOF | ITGB1, ITGA1, ITGAV | SMN1; SMN2 2217/4885MEN1 2072/4885KMT2A 3333/4885 |
| US-12036209-B2 | Compounds and methods for the targeted degradation of Interleukin-1 receptor-associated kinase 4 polypeptides | IRAK1, IRAK4, IRAK2 | SMN1; SMN2 1811/4885MEN1 2168/4885KMT2A 2172/4885 |
| US-11857519-B2 | Compounds and methods for the targeted degradation of enhancer of zeste homolog 2 polypeptide | CRBN, MDM2, VHL | SMN1; SMN2 881/4885MEN1 1376/4885KMT2A 754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.