Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6219140 | 0.83 | BAZ2B (0.41) | NPC1CA12CA1CA2CA9 | |
| SCHEMBL6219513 | 0.82 | GRIK1 (0.33) | LMNA | |
| SCHEMBL6217982 | 0.82 | LMNA (0.31) | LMNA | |
| SCHEMBL6220482 | 0.77 | — | — | |
| SCHEMBL8592597 | 0.75 | NOTUM (0.35) | NPC1RAB9A | |
| SCHEMBL30940103 | 0.75 | KMO (0.32) | — | |
| SCHEMBL9312250 | 0.74 | KMO (0.32) | CA12CA9 | |
| SCHEMBL16793130 | 0.74 | POLB (0.37) | — | |
| SCHEMBL2413504 | 0.73 | SCN9A (0.37) | — | |
| SCHEMBL8687627 | 0.72 | DRD1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1989003825-A1 | HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT (CH) | 1989-05-05 | — | — | WO | disclosed |