SCHEMBL10482000

SCHEMBL10482000

O=S(=O)(CCO)Cc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
PRSS1 P07477 2/20 0.50
PRSS2 P07478 2/20 0.50
PRSS3 P35030 2/20 0.50
FAAH O00519 1/20 0.50
ELANE P08246 1/20 0.50
PRTN3 P24158 1/20 0.50
CA5A P35218 1/20 0.50
CA9 Q16790 1/20 0.50
MMP1 P03956 1/20 0.50
MMP2 P08253 1/20 0.50
MMP9 P14780 1/20 0.50
MMP8 P22894 1/20 0.50
MMP13 P45452 1/20 0.50
ALDH1A1 P00352 4/20 0.46
POLB P06746 2/20 0.46
KMT2A Q03164 4/20 0.46
HSP90AA1 P07900 1/20 0.46
F2 P00734 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9574362 0.89 KMT2A (0.50) CA1CA2CA5ACA9MMP1
SCHEMBL3920142 0.86 CA2 (0.46) CA1CA2PRSS1PRSS2PRSS3
SCHEMBL9574482 0.85 KMT2A (0.41) CA1CA2PRSS1PRSS2PRSS3
SCHEMBL4302784 0.84 CA2 (0.46) CA1CA2PRSS1PRSS2PRSS3
SCHEMBL11209270 0.84 POLB (0.47) CA1CA2PRSS1PRSS2PRSS3
SCHEMBL88641 0.81 CA2 (0.64) CA1CA2PRSS1PRSS2PRSS3
SCHEMBL9180265 0.81 CA2 (0.58) CA1CA2CA9MMP1MMP8
Propanol SCHEMBL8778814 0.81 CA1 (0.48) CA1CA2PRSS1PRSS2PRSS3
SCHEMBL8997396 0.80 TSHR (0.50) CA1CA2CA5ACA9ALDH1A1
SCHEMBL3247748 0.80 CA2 (0.62) CA1CA2PRSS1PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0310944-A2 Bisoxethylsulfonylmethyl anilines and process for their preparation HOECHST AKTIENGESELLSCHAFT (DE) 1989-04-12 EP disclosed
US-4659370-A Substituted phenoxypropionates and herbicidal compositions containing same and their herbicidal use NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1987-04-21 US disclosed
US-4614536-A Certain pyridyloxy-phenoxy-propionate derivatives, herbicidal compositions containing same and their herbicidal method of use NIHON TOKUSHU NOYAKU SEIZO, K.K. (JP) 1986-09-30 US disclosed
EP-0092112-B1 SUBSTITUTED PHENOXY PROPIONATES NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1985-03-06 EP disclosed
US-4500346-A Substituted phenoxypropionates and herbicidal compositions containing same and their herbicidal use NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1985-02-19 US disclosed
EP-0092112-A1 Substituted phenoxy propionates NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1983-10-26 EP disclosed