Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.42 |
| ▸ | CA3 | P07451 | 2/20 | 0.42 |
| ▸ | CA6 | P23280 | 2/20 | 0.42 |
| ▸ | CA5A | P35218 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11581819 | 0.86 | TSHR (0.58) | TSHRHSD17B10KMT2AALDH1A1TP53 | |
| SCHEMBL9574362 | 0.86 | KMT2A (0.50) | KMT2AALDH1A1TP53CA12CA1 | |
| SCHEMBL14426992 | 0.84 | ALDH1A1 (0.55) | TSHRHSD17B10KMT2AALDH1A1TP53 | |
| SCHEMBL1018823 | 0.81 | ALDH1A1 (0.61) | TSHRHSD17B10KMT2AALDH1A1TP53 | |
| SCHEMBL10482000 | 0.80 | CA1 (0.50) | HSD17B10KMT2AALDH1A1CA1CA2 | |
| SCHEMBL10624745 | 0.80 | FOLH1 (0.53) | KMT2ACA1CA2CA9CYP2C19 | |
| SCHEMBL3237371 | 0.79 | TSHR (0.56) | TSHRHSD17B10KMT2AALDH1A1TP53 | |
| SCHEMBL15618996 | 0.78 | KMT2A (0.54) | TSHRHSD17B10KMT2AALDH1A1SRD5A2 | |
| SCHEMBL15568656 | 0.77 | KMT2A (0.66) | TSHRKMT2AALDH1A1TP53CA1 | |
| SCHEMBL15568723 | 0.77 | KMT2A (0.43) | KMT2ACA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500024-A | DISCOLORATION INHIBITION; INTRAOCULAR AND CONTACT LENSES; BONDED TO POLYMER | CIBA-GEIGY CORPORATION (US) | 1996-03-19 | — | — | US | disclosed |
| US-5399692-A | Ultraviolet absorbing benzophenone sulfonic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1995-03-21 | — | — | US | disclosed |
| US-5298033-A | An absorber bonded to lens formed of hydroxyethyl methacrylate | CIBA-GEIGY CORPORATION (US) | 1994-03-29 | — | — | US | disclosed |
| US-4719053-A | FOR DYES | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-01-12 | — | — | US | disclosed |
| US-4473498-A | Water-soluble, fiber-reactive organic dyestuffs containing a β-chloro-ethylsulfonyl-methyl-benzoic acid amide group | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-09-25 | — | — | US | disclosed |