Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 14/20 | 1.00 |
| ▸ | CYSLTR1 | Q9Y271 | 14/20 | 1.00 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10482282 | 1.00 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1PLA2G4B | |
| SCHEMBL10482263 | 0.83 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1 | |
| SCHEMBL2949664 | 0.76 | CYSLTR2 (0.61) | CYSLTR2CYSLTR1PLA2G4B | |
| SCHEMBL20231594 | 0.76 | KDM4E (0.66) | CYSLTR2CYSLTR1PLA2G4B | |
| SCHEMBL20231599 | 0.76 | KDM4E (0.66) | CYSLTR2CYSLTR1PLA2G4B | |
| SCHEMBL10482248 | 0.76 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1 | |
| SCHEMBL10482137 | 0.76 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1 | |
| SCHEMBL11603858 | 0.75 | ALOX5 (0.61) | CYSLTR2CYSLTR1PLA2G4B | |
| SCHEMBL25456542 | 0.75 | PPARA (0.69) | CYSLTR2CYSLTR1PLA2G4B | |
| SCHEMBL17345292 | 0.75 | PPARA (0.69) | CYSLTR2CYSLTR1PLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4730005-A | DITHIA-ALKANEDIOIC ACIDS | SMITHKLINE BECKMAN CORPORATION (US) | 1988-03-08 | — | — | US | claimed |
| EP-0168902-B1 | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BECKMAN CORPORATION (US) | 1987-09-30 | — | — | EP | claimed |
| EP-0168902-A1 | Leukotriene antagonists | SMITHKLINE BECKMAN CORPORATION (US) | 1986-01-22 | — | — | EP | claimed |
| US-4871771-A | PHENYL SUBSTITUTED-DITHIA-ALKANEDIOIC ACIDS | SMITHKLINE BECKMAN CORPORATION (US) | 1989-10-03 | — | — | US | disclosed |
| EP-0327306-A2 | Leukotriene B4 antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1989-08-09 | — | — | EP | disclosed |
| US-4730005-A | DITHIA-ALKANEDIOIC ACIDS | SMITHKLINE BECKMAN CORPORATION (US) | 1988-03-08 | — | — | US | disclosed |
| EP-0168902-B1 | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BECKMAN CORPORATION (US) | 1987-09-30 | — | — | EP | disclosed |
| EP-0168902-A1 | Leukotriene antagonists | SMITHKLINE BECKMAN CORPORATION (US) | 1986-01-22 | — | — | EP | disclosed |