Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MDM4 | O15151 | 2/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CMA1 | P23946 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1050745 | 1.00 | METTL3 (0.50) | METTL3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL12960113 | 0.93 | METTL3 (0.48) | METTL3ALDH1A1KDM4EPOLBTSHR | |
| SCHEMBL12960096 | 0.92 | METTL3 (0.60) | METTL3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL1048231 | 0.92 | METTL3 (0.60) | METTL3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL1050734 | 0.85 | METTL3 (0.72) | METTL3MAPTPOLBMDM2TP53 | |
| SCHEMBL1052890 | 0.85 | METTL3 (0.72) | METTL3MAPTPOLBMDM2TP53 | |
| SCHEMBL11948614 | 0.84 | METTL3 (0.58) | METTL3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL16850607 | 0.84 | METTL3 (0.58) | METTL3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL17549681 | 0.84 | METTL3 (0.68) | METTL3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL16385502 | 0.84 | METTL3 (0.68) | METTL3ALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011004389-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF ELVITEGRAVIR | MATRIX LABORATORIES LTD (IN) | 2011-01-13 | — | — | WO | disclosed |