Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 1/20 | 0.60 |
| ▸ | RORC | P51449 | 2/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TOP1 | P11387 | 2/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | CFD | P00746 | 2/20 | 0.31 |
| ▸ | VDR | P11473 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12960096 | 1.00 | METTL3 (0.60) | METTL3RORCEP300CREBBPGAA | |
| SCHEMBL1050734 | 0.92 | METTL3 (0.72) | METTL3RORCEP300CREBBPGAA | |
| SCHEMBL1052890 | 0.92 | METTL3 (0.72) | METTL3RORCEP300CREBBPGAA | |
| SCHEMBL1048227 | 0.92 | METTL3 (0.50) | METTL3KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL1050745 | 0.92 | METTL3 (0.50) | METTL3KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL12960113 | 0.90 | METTL3 (0.48) | METTL3KDM4EALDH1A1 | |
| SCHEMBL12957304 | 0.84 | METTL3 (0.69) | METTL3GAAHTTTOP1KDM4E | |
| Biphenyl SCHEMBL1052588 | 0.83 | METTL3 (0.70) | METTL3GAAHTTTOP1KDM4E | |
| SCHEMBL2280106 | 0.83 | METTL3 (0.69) | METTL3GAAHTTTOP1KDM4E | |
| SCHEMBL1050772 | 0.82 | METTL3 (0.81) | METTL3GAAHTTTOP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011004389-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF ELVITEGRAVIR | MATRIX LABORATORIES LTD (IN) | 2011-01-13 | — | — | WO | disclosed |