Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566577 | 0.91 | NPC1 (0.54) | MEN1KMT2AKCNMA1MAPK1L3MBTL1 | |
| SCHEMBL9566451 | 0.88 | SMN1; SMN2 (0.56) | MEN1KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL10483366 | 0.87 | NPC1 (0.51) | MEN1KMT2AKCNMA1L3MBTL1NPC1 | |
| SCHEMBL10822593 | 0.85 | NPC1 (0.48) | MEN1KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL9566457 | 0.84 | SMN1; SMN2 (0.55) | MEN1KMT2AKCNMA1MAPK1NPC1 | |
| SCHEMBL9566631 | 0.83 | MEN1 (0.56) | MEN1KMT2AKCNMA1MAPK1L3MBTL1 | |
| SCHEMBL9566558 | 0.82 | NPC1 (0.49) | MEN1KMT2AKCNMA1L3MBTL1NPC1 | |
| SCHEMBL9566608 | 0.81 | NPC1 (0.58) | MEN1KMT2AKCNMA1L3MBTL1NPC1 | |
| SCHEMBL11591466 | 0.81 | HDAC1 (0.60) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11591085 | 0.81 | HDAC1 (0.60) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4874762-A | TREATING DEMENTIA | NIPPON SHINYAKU CO., LTD. (JP) | 1989-10-17 | — | — | US | claimed |
| US-4874762-A | TREATING DEMENTIA | NIPPON SHINYAKU CO., LTD. (JP) | 1989-10-17 | — | — | US | disclosed |