⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1048341 | 0.86 | — | — | |
| SCHEMBL1046461 | 0.74 | NPC1 (0.32) | — | |
| SCHEMBL1047204 | 0.73 | NPC1 (0.34) | — | |
| SCHEMBL1044862 | 0.70 | — | — | |
| SCHEMBL19405578 | 0.68 | TSHR (0.31) | — | |
| SCHEMBL17164313 | 0.67 | LTA4H (0.33) | — | |
| SCHEMBL8165780 | 0.66 | NPC1 (0.39) | — | |
| SCHEMBL8426122 | 0.64 | NPC1 (0.33) | — | |
| SCHEMBL1050194 | 0.64 | — | — | |
| SCHEMBL1383 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120178617-A1 | Preparation of Supported Silyl-Capped Silica-Bound Anion Activators and Associated Catalysts | EXXONMOBIL CHEMICAL PATENTS INC. | 2012-07-12 | — | — | US | disclosed |
| US-8163854-B2 | Preparation of supported silyl-capped silica-bound anion activators and associated catalysts | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2012-04-24 | — | — | US | disclosed |
| US-20110015357-A1 | Preparation of Supported Silyl-Capped Silica-Bound Anion Activators and Associated Catalysts | EXXONMOBIL CHEMICAL PATENTS INC. | 2011-01-20 | — | — | US | disclosed |
| US-7847038-B2 | Preparation of supported silyl-capped silica-bound anion activators and associated catalysts | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-12-07 | — | — | US | disclosed |
| CN-101687188-A | Preparation of supported silyl-capped silica silica-bound anion activators and associated catalysts | EXXONMOBIL CHEM PATENTS INC | 2010-03-31 | — | — | CN | disclosed |
| WO-2009012022-A1 | PREPARATION OF SUPPORTED SILYL-CAPPED SILICA SILICA-BOUND ANION ACTIVATORS AND ASSOCIATED CATALYSTS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2009-01-22 | — | — | WO | disclosed |
| US-20090018290-A1 | Preparation of Supported Silyl-Capped Silica-Bound Anion Activators and Associated Catalysts | EXXONMOBIL CHEMICAL PATENTS INC. | 2009-01-15 | — | — | US | disclosed |