Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1047204 | 0.86 | NPC1 (0.34) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL1050194 | 0.86 | — | — | |
| SCHEMBL1050447 | 0.77 | — | — | |
| SCHEMBL8165780 | 0.76 | NPC1 (0.39) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL1052275 | 0.75 | — | — | |
| SCHEMBL1049005 | 0.75 | — | — | |
| SCHEMBL1048372 | 0.74 | — | — | |
| SCHEMBL8356704 | 0.74 | — | — | |
| SCHEMBL1050797 | 0.72 | — | — | |
| SCHEMBL26375129 | 0.72 | TAS1R3 (0.38) | NPC1HPGDMAPK1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120178617-A1 | Preparation of Supported Silyl-Capped Silica-Bound Anion Activators and Associated Catalysts | EXXONMOBIL CHEMICAL PATENTS INC. | 2012-07-12 | — | — | US | disclosed |
| US-8163854-B2 | Preparation of supported silyl-capped silica-bound anion activators and associated catalysts | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2012-04-24 | — | — | US | disclosed |
| US-20110015357-A1 | Preparation of Supported Silyl-Capped Silica-Bound Anion Activators and Associated Catalysts | EXXONMOBIL CHEMICAL PATENTS INC. | 2011-01-20 | — | — | US | disclosed |
| US-7847038-B2 | Preparation of supported silyl-capped silica-bound anion activators and associated catalysts | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-12-07 | — | — | US | disclosed |
| CN-101687188-A | Preparation of supported silyl-capped silica silica-bound anion activators and associated catalysts | EXXONMOBIL CHEM PATENTS INC | 2010-03-31 | — | — | CN | disclosed |
| WO-2009012022-A1 | PREPARATION OF SUPPORTED SILYL-CAPPED SILICA SILICA-BOUND ANION ACTIVATORS AND ASSOCIATED CATALYSTS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2009-01-22 | — | — | WO | disclosed |
| US-20090018290-A1 | Preparation of Supported Silyl-Capped Silica-Bound Anion Activators and Associated Catalysts | EXXONMOBIL CHEMICAL PATENTS INC. | 2009-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018290-A1 | Preparation of Supported Silyl-Capped Silica-Bound Anion Activators and Associated Catalysts | TLL2, ESPL1, CCNL2 | NPC1 4253/4885HPGD 3154/4885MAPK1 2730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.