Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 3/20 | 0.38 |
| ▸ | CCND1 | P24385 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.32 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2523223 | 0.92 | CDK4 (0.32) | CDK4CCND1CYP3A4TSHRPIK3CA | |
| SCHEMBL77591 | 0.79 | TSHR (0.40) | CYP3A4TSHRPIK3CAALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL28280347 | 0.77 | CYP3A4 (0.39) | CYP3A4TSHRPIK3CAALDH1A1LMNA | |
| SCHEMBL5964838 | 0.74 | MAOB (0.48) | CYP3A4TSHRPIK3CAALDH1A1TRPA1 | |
| SCHEMBL5451938 | 0.73 | XDH (0.44) | CDK4CCND1TSHRALDH1A1TRPA1 | |
| SCHEMBL5479284 | 0.72 | CDK4 (0.35) | CDK4CCND1ALDH1A1TRPA1LMNA | |
| SCHEMBL9033292 | 0.71 | CYP19A1 (0.47) | MAPT | |
| SCHEMBL27589735 | 0.71 | CYP19A1 (0.47) | ALDH1A1TRPA1ALOX5KDM4E | |
| SCHEMBL6846966 | 0.71 | CDK4 (0.34) | CDK4CCND1CYP3A4TSHRALDH1A1 | |
| SCHEMBL7258077 | 0.71 | ALDH1A1 (0.45) | CDK4CCND1CYP3A4TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993253-B2 | Protease detection | MOLOGIC LTD (GB) | 2015-03-31 | — | — | US | claimed |
| US-8361386-B2 | Enzyme detection | MOLOGIC LTD (GB) | 2013-01-29 | — | — | US | claimed |
| EP-2205681-B1 | DYE COMPOSITION COMPRISING AT LEAST ONE COLORLESS DISULFIDE/THIOL PRECURSOR, AND DYEING PROCESS USING THE COMPOSITION | OREAL (FR) | 2011-08-31 | — | — | EP | claimed |
| US-7214248-B1 | Multi-component kit and method for temporarily dyeing and later decolorizing hair | WELLA AG (DE) | 2007-05-08 | — | — | US | claimed |
| EP-1227786-B1 | AGENT FOR DYEING FIBRES COMPRISING AN INDOLINE/INDOLIUM DERIVATIVE | WELLA AG (DE) | 2005-08-24 | — | — | EP | claimed |
| US-6652601-B2 | For dyeing and subsequently decolorizing fibers such as keratin fibers | WELLA AKTIENGESELLSCHAFT (DE) | 2003-11-25 | — | — | US | claimed |
| US-5565328-A | COLORIMETRIC ANALYSIS WITH FLUOROMETRIC READER USING SUITABLE FLUOROPHORE | DADE INTERNATIONAL INC. (US) | 1996-10-15 | — | — | US | claimed |
| CN-116577310-A | Viscosity detection method and application thereof | 山东第一医科大学(山东省医学科学院) | 2023-08-11 | — | — | CN | disclosed |
| CN-114354523-A | Rapid comparison method for content of procyanidine in radix tetrastigme leaves of different provenances | 杭州市农业科学研究院 | 2022-04-15 | — | — | CN | disclosed |
| EP-3004236-B1 | COLOR-STABLE THERMOPLASTIC COMPOSITION | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2018-07-18 | — | — | EP | disclosed |
| US-9708465-B2 | Color-stable thermoplastic composition | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2017-07-18 | — | — | US | disclosed |
| EP-3004236-A1 | COLOR-STABLE THERMOPLASTIC COMPOSITION | SABIC Global Technologies B.V. (NL) | 2016-04-13 | — | — | EP | disclosed |
| US-20140357768-A1 | COLOR-STABLE THERMOPLASTIC COMPOSITION | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2014-12-04 | — | — | US | disclosed |
| WO-2009040354-A1 | DYE COMPOSITION COMPRISING AT LEAST ONE COLORLESS DISULFIDE/THIOL PRECURSOR, AND DYEING PROCESS USING THE COMPOSITION | L'OREAL (FR) | 2009-04-02 | — | — | WO | disclosed |
| CN-100457050-C | Diagnostic test device and method of using same | KIMBERLY CLARK CO (US) | 2009-02-04 | — | — | CN | disclosed |
| WO-2008140452-A1 | NOVEL HYDRAZONE-BASED AND OXIME-BASED FLUORESCENT AND CHROMOPHORIC/PRO-FLUORESCENT AND PRO-CHROMOPHORIC REAGENTS AND LINKERS | SOLULINK, INC. (US) | 2008-11-20 | — | — | WO | disclosed |
| US-20080221343-A1 | Labeled biomolecules of chromophore or the fluorophore incorporated into the linker between a reactive linking moiety and a biotin molecule; proteins, nucleic acids | AUDAX PRIVATE DEBT LLC, AS AGENT | 2008-09-11 | — | — | US | disclosed |
| WO-2008104680-A2 | MEDIUM FOR DETECTING AND/OR IDENTIFYING BACTERIA | bioMérieux (FR) | 2008-09-04 | — | — | WO | disclosed |
| CN-1870943-A | Diagnostic test device and method of using same | KIMBERLY CLARK CO (US) | 2006-11-29 | — | — | CN | disclosed |
| US-7026336-B1 | 4-pyridinylimidazol-2-ylhydrocarbyl amine, (thio)urea, carbamic acid or sulfonamide derivatives, e.g., (2-(4-(4-Chloro-3-methoxy-phenyl)-5-pyridin-4-yl-1H-imidazol-2-yl)-2-methyl-propyl)-carbamic acid tert-butyl ester; Raf kinase inhibitors for the treatment of neurotraumatic diseases | SMITHKLINE BEECHAM P.L.C. (GB) | 2006-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221343-A1 | Labeled biomolecules of chromophore or the fluorophore incorporated into the linker between a reactive linking moiety and a biotin molecule; proteins, nucleic acids | RRP12, MRPS22, HBG2 | CDK4 1655/4885CCND1 745/4885CYP3A4 3091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.