Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOX | P28300 | 1/20 | 0.59 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.59 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | MC4R | P32245 | 2/20 | 0.47 |
| ▸ | MC5R | P33032 | 2/20 | 0.47 |
| ▸ | MC3R | P41968 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
| ▸ | FERMT2 | Q96AC1 | 3/20 | 0.38 |
| ▸ | GSK3A | P49840 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10483879 | 0.93 | LOX (0.56) | LOXLOXL3LOXL2RECQLMC4R | |
| SCHEMBL7995987 | 0.83 | RECQL (0.50) | LOXLOXL3LOXL2RECQLCHRM2 | |
| SCHEMBL10483895 | 0.79 | LOXL2 (0.59) | LOXL2MC4RMC5RMC3RCHRM2 | |
| SCHEMBL10484162 | 0.79 | MC4R (0.47) | LOXLOXL3LOXL2MC4RMC5R | |
| SCHEMBL10484031 | 0.79 | MC4R (0.47) | MC4RMC5RMC3RCHRM2ROCK1 | |
| SCHEMBL22972214 | 0.79 | RECQL (0.53) | LOXLOXL3LOXL2RECQLROCK1 | |
| SCHEMBL22878184 | 0.79 | RECQL (0.53) | LOXLOXL3LOXL2RECQLGHSR | |
| SCHEMBL10483844 | 0.78 | MC4R (0.49) | LOXLOXL3LOXL2RECQLMC4R | |
| SCHEMBL20641351 | 0.77 | BCHE (0.48) | LOXLOXL3LOXL2RECQL | |
| SCHEMBL12720918 | 0.76 | LOXL2 (0.70) | LOXLOXL3LOXL2RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4812571-A | NITROMETHYLENE COMPOUNDS | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1989-03-14 | — | — | US | disclosed |
| US-4774247-A | Nitromethylene derivative insecticides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1988-09-27 | — | — | US | disclosed |
| US-4678795-A | 1-pyridylmethyl-2-nitromethylene-1,3-diazacycloalkane insecticides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1987-07-07 | — | — | US | disclosed |
| EP-0192060-A1 | Heterocyclic compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1986-08-27 | — | — | EP | disclosed |
| EP-0163855-A1 | Nitromethylene derivatives, intermediates, and process for their preparation as insecticides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1985-12-11 | — | — | EP | disclosed |