Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOX | P28300 | 1/20 | 0.56 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.56 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.56 |
| ▸ | MC4R | P32245 | 2/20 | 0.50 |
| ▸ | MC5R | P33032 | 2/20 | 0.50 |
| ▸ | MC3R | P41968 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.42 |
| ▸ | FERMT2 | Q96AC1 | 2/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GHSR | Q92847 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10483974 | 0.93 | LOX (0.59) | LOXLOXL3LOXL2MC4RMC5R | |
| SCHEMBL10483900 | 0.81 | LOXL2 (0.56) | LOXL2MC4RMC5RMC3RCHRM2 | |
| SCHEMBL10483909 | 0.81 | MC4R (0.50) | MC4RMC5RMC3RCHRM2ROCK1 | |
| SCHEMBL7995987 | 0.80 | RECQL (0.50) | LOXLOXL3LOXL2RECQLCHRM2 | |
| SCHEMBL10483951 | 0.80 | MC4R (0.51) | MC4RMC5RMC3RRECQLCHRM2 | |
| SCHEMBL20641351 | 0.78 | BCHE (0.48) | LOXLOXL3LOXL2RECQLSMN1; SMN2 | |
| SCHEMBL22972214 | 0.76 | RECQL (0.53) | LOXLOXL3LOXL2RECQLROCK1 | |
| SCHEMBL22878184 | 0.76 | RECQL (0.53) | LOXLOXL3LOXL2RECQLPOLB | |
| SCHEMBL21591559 | 0.76 | NOS1 (0.57) | CHRM2GSK3AGSK3B | |
| SCHEMBL10734543 | 0.75 | ALDH1A1 (0.56) | LOXL2MC4RMC5RMC3RCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4812571-A | NITROMETHYLENE COMPOUNDS | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1989-03-14 | — | — | US | disclosed |
| US-4774247-A | Nitromethylene derivative insecticides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1988-09-27 | — | — | US | disclosed |
| US-4678795-A | 1-pyridylmethyl-2-nitromethylene-1,3-diazacycloalkane insecticides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1987-07-07 | — | — | US | disclosed |
| EP-0163855-A1 | Nitromethylene derivatives, intermediates, and process for their preparation as insecticides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1985-12-11 | — | — | EP | disclosed |