Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10484249 | 1.00 | LMNA (0.39) | LMNAALDH1A1KDM4E | |
| SCHEMBL10648011 | 1.00 | LMNA (0.39) | LMNAALDH1A1KDM4E | |
| SCHEMBL9509889 | 0.84 | LMNA (0.41) | LMNAALDH1A1KDM4E | |
| SCHEMBL4814642 | 0.77 | LMNA (0.35) | LMNAALDH1A1 | |
| SCHEMBL8584442 | 0.75 | ALDH1A1 (0.45) | ALDH1A1 | |
| SCHEMBL6324974 | 0.74 | LMNA (0.41) | LMNAALDH1A1 | |
| SCHEMBL6187349 | 0.74 | LMNA (0.33) | LMNA | |
| SCHEMBL6672110 | 0.73 | LMNA (0.39) | LMNA | |
| SCHEMBL17077957 | 0.71 | LMNA (0.31) | LMNA | |
| SCHEMBL92233 | 0.71 | LMNA (0.48) | LMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4829090-A | SECONDARY AMINES, ANTITUMOR | BURROUGHS WELLCOME CO. (US) | 1989-05-09 | — | — | US | disclosed |
| US-4820873-A | ANTITUMOR AGENTS | BURROUGHS WELLCOME CO. (US) | 1989-04-11 | — | — | US | disclosed |
| US-4810727-A | ANTITUMOR | BURROUGHS WELLCOME CO. (US) | 1989-03-07 | — | — | US | disclosed |
| US-4808625-A | ANTITUMOR AGENTS | BURROUGHS WELLCOME CO. (US) | 1989-02-28 | — | — | US | disclosed |
| US-4808632-A | ANTITUMOR AGENTS | BURROUGHS WELLCOME CO. (US) | 1989-02-28 | — | — | US | disclosed |
| US-4803222-A | ANTITUMOR AGENTS | BURROUGHS WELLCOME CO. (US) | 1989-02-07 | — | — | US | disclosed |
| US-4803221-A | Anthracene derivatives | BURROUGHS WELLCOME CO. (US) | 1989-02-07 | — | — | US | disclosed |
| EP-0125701-B1 | POLYCYCLIC AROMATIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1988-08-03 | — | — | EP | disclosed |
| US-4720587-A | ANTITUMOR AGENTS | BURROUGHS WELLCOME CO. (US) | 1988-01-19 | — | — | US | disclosed |
| US-4719048-A | ANTITUMOR | BURROUGHS WELLCOME CO. (US) | 1988-01-12 | — | — | US | disclosed |
| US-4719046-A | ANTITUMOR | BURROUGHS WELLCOME CO. (US) | 1988-01-12 | — | — | US | disclosed |
| US-4719236-A | ANTITUMOR | BURROUGHS WELLCOME CO. (US) | 1988-01-12 | — | — | US | disclosed |
| US-4719055-A | ANTITUMOR | BURROUGHS WELLCOME CO. (US) | 1988-01-12 | — | — | US | disclosed |
| US-4719049-A | ANTITUMOR | BURROUGHS WELLCOME CO. (US) | 1988-01-12 | — | — | US | disclosed |
| EP-0125702-B1 | POLYCYCLIC AROMATIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1987-08-12 | — | — | EP | disclosed |
| EP-0125701-A2 | Polycyclic aromatic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-11-21 | — | — | EP | disclosed |
| EP-0125702-A2 | Polycyclic aromatic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-11-21 | — | — | EP | disclosed |