Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | RARA | P10276 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.34 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9812415 | 1.00 | HIF1A (0.39) | HIF1ARARARARBMAPTTHRB | |
| SCHEMBL9812514 | 0.97 | HIF1A (0.41) | HIF1AMAOBALDH1A1KMT2APARP10 | |
| SCHEMBL9812523 | 0.97 | HIF1A (0.41) | HIF1AMAOBALDH1A1KMT2APARP10 | |
| SCHEMBL9812709 | 0.90 | TP53 (0.41) | RARARARBMAPTTHRBALDH1A1 | |
| SCHEMBL9812702 | 0.90 | TP53 (0.41) | RARARARBMAPTTHRBALDH1A1 | |
| SCHEMBL9812404 | 0.88 | CYP11B1 (0.40) | MAPTMAOBNPC1RAB9A | |
| SCHEMBL9812395 | 0.88 | CYP11B1 (0.40) | MAPTMAOBNPC1RAB9A | |
| SCHEMBL10484276 | 0.88 | KMT2A (0.39) | HIF1AMAPTSLC6A3CYP1A2CYP2C19 | |
| SCHEMBL10484281 | 0.88 | KMT2A (0.39) | HIF1AMAPTSLC6A3CYP1A2CYP2C19 | |
| SCHEMBL10484284 | 0.87 | CYP2C9 (0.47) | HIF1AMAPTALDH1A1KMT2APARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219975-B1 | FLUOROPHENYLCYCLOHEXANE DERIVATIVE | Chisso Corporation (JP) | 1991-07-03 | — | — | EP | disclosed |
| US-4855076-A | Fluorophenylcyclohexane derivative | CHISSO CORPORATION (JP) | 1989-08-08 | — | — | US | disclosed |
| EP-0219975-A1 | Fluorophenylcyclohexane derivative | Chisso Corporation (JP) | 1987-04-29 | — | — | EP | disclosed |