Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10484344 | 1.00 | PTGS1 (0.48) | PTGS1ALDH1A1LMNASMN1; SMN2NFE2L2 | |
| SCHEMBL10484007 | 0.94 | CES2 (0.47) | PTGS1ALDH1A1LMNASMN1; SMN2NFE2L2 | |
| SCHEMBL10484146 | 0.94 | CES2 (0.47) | PTGS1ALDH1A1LMNASMN1; SMN2NFE2L2 | |
| SCHEMBL10484147 | 0.94 | CES2 (0.47) | PTGS1ALDH1A1LMNASMN1; SMN2NFE2L2 | |
| SCHEMBL10484009 | 0.94 | CES2 (0.47) | PTGS1ALDH1A1LMNASMN1; SMN2NFE2L2 | |
| SCHEMBL10484187 | 0.81 | CES2 (0.47) | ALDH1A1LMNASMN1; SMN2KDM4EESR1 | |
| SCHEMBL10484201 | 0.81 | CES2 (0.47) | ALDH1A1LMNASMN1; SMN2KDM4EESR1 | |
| SCHEMBL10484164 | 0.78 | ESRRG (0.41) | PTGS1ALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL10484157 | 0.78 | ESRRG (0.41) | PTGS1ALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL10484465 | 0.78 | MAPT (0.46) | PTGS1ALDH1A1LMNASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4806685-A | EXERTS VARIOUS EFFECTS ON ENDOCRINOUS SYSTEM OF RATS; INHIBITS GROWTH OF MAMMARY TUMORS | GYOGYSZERKUTATO INTEEZET/PHARMACEUTICAL RESEARCH INSTITUTE (HU) | 1989-02-21 | — | — | US | disclosed |