Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRG | P62508 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 5/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10484164 | 1.00 | ESRRG (0.41) | ESRRGKDM4EALDH1A1THRBNPSR1 | |
| SCHEMBL10484130 | 0.85 | ESR1 (0.53) | ESRRGKDM4EALDH1A1L3MBTL1MAPT | |
| SCHEMBL10484336 | 0.85 | ESR1 (0.53) | ESRRGKDM4EALDH1A1L3MBTL1MAPT | |
| SCHEMBL10484146 | 0.85 | CES2 (0.47) | KDM4EALDH1A1NPSR1LMNAMAPK1 | |
| SCHEMBL10484009 | 0.85 | CES2 (0.47) | KDM4EALDH1A1NPSR1LMNAMAPK1 | |
| SCHEMBL10484147 | 0.85 | CES2 (0.47) | KDM4EALDH1A1NPSR1LMNAMAPK1 | |
| SCHEMBL10484007 | 0.85 | CES2 (0.47) | KDM4EALDH1A1NPSR1LMNAMAPK1 | |
| SCHEMBL10484100 | 0.84 | ESR1 (0.56) | ESRRGKDM4EALDH1A1NPSR1LMNA | |
| SCHEMBL10484096 | 0.84 | ESR1 (0.56) | ESRRGKDM4EALDH1A1NPSR1LMNA | |
| SCHEMBL10484213 | 0.82 | ESRRG (0.43) | ESRRGKDM4EALDH1A1THRBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4806685-A | EXERTS VARIOUS EFFECTS ON ENDOCRINOUS SYSTEM OF RATS; INHIBITS GROWTH OF MAMMARY TUMORS | GYOGYSZERKUTATO INTEEZET/PHARMACEUTICAL RESEARCH INSTITUTE (HU) | 1989-02-21 | — | — | US | disclosed |