Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL10484352 | 1.00 | LMNA (0.57) | LMNATSHRTP53TDP1HSD17B10 | |
| Benzene SCHEMBL1744419 | 1.00 | LMNA (0.57) | LMNATSHRTP53TDP1HSD17B10 | |
| Benzene SCHEMBL7286716 | 0.84 | LMNA (0.40) | LMNATSHRTP53ALDH1A1 | |
| Benzene SCHEMBL9453755 | 0.80 | TSHR (0.56) | LMNATSHRTP53TDP1HSD17B10 | |
| Benzene SCHEMBL11221164 | 0.80 | LMNA (0.36) | LMNATSHRALDH1A1 | |
| Chloroform SCHEMBL88 | 0.76 | — | — | |
| Chloroform SCHEMBL30536988 | 0.76 | — | — | |
| Benzene SCHEMBL252016 | 0.76 | TSHR (0.67) | LMNATSHRTP53TDP1ALDH1A1 | |
| Chloroform SCHEMBL10950487 | 0.76 | LMNA (1.00) | LMNATSHRTDP1HSD17B10ALDH1A1 | |
| Chloroform SCHEMBL2084455 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4882323-A | ANTIARRYTHMIA AGENT INTERMEDIATES | AMERICAN HOME PRODUCTS (US) | 1989-11-21 | — | — | US | disclosed |