Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL9453755 | 0.94 | TSHR (0.56) | TSHRALDH1A1TP53LMNATDP1 | |
| SCHEMBL126 | 0.82 | — | — | |
| SCHEMBL11523834 | 0.82 | — | — | |
| SCHEMBL5728116 | 0.82 | — | — | |
| SCHEMBL5438089 | 0.82 | — | — | |
| Benzene SCHEMBL8111616 | 0.76 | TSHR (0.43) | TSHRALDH1A1TP53LMNATDP1 | |
| SCHEMBL8462179 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL4728720 | 0.76 | — | — | |
| Chloromethane SCHEMBL5050446 | 0.76 | — | — | |
| SCHEMBL22394670 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-55108828-A | — | — | None | — | — | JP | disclosed |
| CN-111100250-B | Aqueous acrylate resin, preparation method thereof and one-component rapid film-forming adhesive composition containing same | 万华化学集团股份有限公司 | 2022-08-02 | — | — | CN | disclosed |
| CN-111100250-A | Aqueous acrylate resin, preparation method thereof and one-component rapid film-forming adhesive composition containing same | 万华化学集团股份有限公司 | 2020-05-05 | — | — | CN | disclosed |
| CN-108997127-A | A kind of production technology synthesizing 1,3- bis--(2- chloro-trifluoromethyl phenoxy) -4- nitrobenzene | 浙江禾本科技有限公司 | 2018-12-14 | — | — | CN | disclosed |
| CN-108383730-A | 3, the 5- novel nitrated techniques of dinitro -4- chlorobenzotrifluorides | 江苏大华化学工业有限公司 | 2018-08-10 | — | — | CN | disclosed |
| EP-2588455-B1 | 2-QUINOLINYL-ACETIC ACID DERIVATIVES AS HIV ANTIVIRAL COMPOUNDS | GILEAD SCIENCES INC (US) | 2018-04-04 | — | — | EP | disclosed |
| CN-104837337-B | Extruded self-clumping animal litter and method of making extruded self-clumping animal litter | 先锋宠物用品有限责任公司 | 2017-04-12 | — | — | CN | disclosed |
| US-9296758-B2 | 2-quinolinyl-acetic acid derivatives as HIV antiviral compounds | GILEAD SCIENCES, INC. (US) | 2016-03-29 | — | — | US | disclosed |
| US-20130210801-A1 | 2-QUINOLINYL-ACETIC ACID DERIVATIVES AS HIV ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2013-08-15 | — | — | US | disclosed |
| EP-2588455-A1 | 2 -QUINOLINYL- ACETIC ACID DERIVATIVES AS HIV ANTIVIRAL COMPOUNDS | Gilead Sciences, Inc. (US) | 2013-05-08 | — | — | EP | disclosed |
| US-8236954-B2 | Processes for preparing benzimidazole thiophenes | GLAXOSMITHKLINE LLC (US) | 2012-08-07 | — | — | US | disclosed |
| WO-2012003498-A1 | 2 -QUINOLINYL- ACETIC ACID DERIVATIVES AS HIV ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2012-01-05 | — | — | WO | disclosed |
| US-20100256376-A1 | Processes For Preparing Benzimidazole Thiophenes | GLAXOSMITHKLINE LLC | 2010-10-07 | — | — | US | disclosed |
| EP-2170871-A2 | PROCESSES FOR PREPARING BENZIMIDAZOLE THIOPHENES | GlaxoSmithKline LLC (US) | 2010-04-07 | — | — | EP | disclosed |
| WO-2009002916-A2 | PROCESSES FOR PREPARING BENZIMIDAZOLE THIOPHENES | SMITHKLINE BEECHAM CORPORATION (US) | 2008-12-31 | — | — | WO | disclosed |
| US-4992151-A | Method for the selective alpha halogenation of alkylaromatic compounds | THE DOW CHEMICAL COMPANY (US) | 1991-02-12 | — | — | US | disclosed |
| US-4831194-A | Process for the preparation of nitrodiaryl sulfoxides | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1989-05-16 | — | — | US | disclosed |
| US-4710323-A | Nitrodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them as active ingredient | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1987-12-01 | — | — | US | disclosed |
| JP-S55108828-A | PREPARATION OF CHLORINATION PRODUCT AND ETHYL BENZENE | SANYO CHEM IND LTD | 1980-08-21 | — | — | JP | disclosed |
| US-4103012-A | CARDIOVASCULAR DISORDERS | LABAZ (FR) | 1978-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256376-A1 | Processes For Preparing Benzimidazole Thiophenes | TPMT, TBKBP1, TYMP | TSHR 595/4885ALDH1A1 902/4885TP53 3000/4885 |
| US-20130210801-A1 | 2-QUINOLINYL-ACETIC ACID DERIVATIVES AS HIV ANTIVIRAL COMPOUNDS | NFATC1, ACIN1, ARF1 | TSHR 4474/4885ALDH1A1 252/4885TP53 3536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.