SCHEMBL10484652

SCHEMBL10484652

Cc1c(N)ccc([N+](=O)[O-])c1C.I[Hg]I

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.50
TDP1 Q9NUW8 6/20 0.48
CYP3A4 P08684 5/20 0.44
ALDH1A1 P00352 5/20 0.44
MEN1 O00255 2/20 0.44
POLB P06746 2/20 0.44
MAPT P10636 2/20 0.44
KMT2A Q03164 2/20 0.44
ALOX15 P16050 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
RECQL P46063 1/20 0.42
LMNA P02545 2/20 0.39
PKM P14618 1/20 0.39
HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1683191 0.92 TSHR (0.57) TSHRTDP1CYP3A4ALDH1A1MEN1
SCHEMBL30503599 0.79 TDP1 (0.71) TSHRTDP1CYP3A4ALDH1A1MAPT
SCHEMBL9719281 0.79 TDP1 (0.71) TSHRTDP1CYP3A4ALDH1A1MAPT
SCHEMBL588286 0.79 TSHR (0.55) TSHRTDP1CYP3A4ALDH1A1MEN1
SCHEMBL2056814 0.79 TSHR (0.60) TSHRTDP1CYP3A4ALDH1A1MEN1
SCHEMBL1635417 0.77 TSHR (0.53) TSHRTDP1CYP3A4ALDH1A1MEN1
SCHEMBL2006430 0.77 TSHR (0.53) TSHRTDP1CYP3A4ALDH1A1MEN1
SCHEMBL30857795 0.77 TSHR (0.53) TSHRTDP1CYP3A4ALDH1A1MEN1
SCHEMBL28038852 0.77 TSHR (0.53) TSHRTDP1CYP3A4ALDH1A1MEN1
SCHEMBL28065463 0.77 TSHR (0.53) TSHRTDP1CYP3A4ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4865944-A FILM SUPPORT, FLUORESENT LAYER OF PHOSPHOR AND BINDER, SILVER HALIDE EMULSION LAYER AND OVERCOATING CONTAINING OXIDATION PROMOTER; SHARPNESS; HIGH SPEED, LOW ENERGY EASTMAN KODAK COMPANY (US) 1989-09-12 US disclosed